PtCl2-catalyzed cycloisomerizations of 5-En-1-yn-3-ol systems

被引：208

作者：

Harrak, Y ^{[1
]}

Blaszykowski, C ^{[1
]}

Bernard, M ^{[1
]}

Cariou, K ^{[1
]}

Mainetti, E ^{[1
]}

Mouriès, V ^{[1
]}

Dhimane, AL ^{[1
]}

Fensterbank, L ^{[1
]}

Malacria, M ^{[1
]}

机构：

[1] Univ Paris 06, CNRS, UMR 7611, Chim Organ Lab, F-75252 Paris 05, France

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2004年 / 126卷 / 28期

关键词：

D O I：

10.1021/ja0474695

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

5-En-1-yn-3-ol substrates bearing a free hydroxyl group or an acyl group are highly versatile partners for PtCl2-catalyzed cycloisomerizations. Electrophilic activation of the alkyne moiety triggers at wish a hydride or an O-acyl migration yielding at the end to regioisomeric keto derivatives. The efficient preparation of Sabina ketone, an important monoterpene precursor, has been worked out. Copyright © 2004 American Chemical Society.

引用

页码：8656 / 8657

页数：2

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