Advanced nanomaterials for use in electrochemical and optical immunoassays of carcinoembryonic antigen. A review

被引：74
作者：
Hasanzadeh, Mohammad [1 ,2 ]
Shadjou, Nasrin [3 ,4 ]
机构：
[1] Tabriz Univ Med Sci, Drug Appl Res Ctr, Tabriz 51664, Iran
[2] Tabriz Univ Med Sci, Pharmaceut Anal Res Ctr, Tabriz 51664, Iran
[3] Urmia Univ, Dept Nanochem, Nano Technol Res Ctr, Orumiyeh, Iran
[4] Urmia Univ, Dept Nanochem, Fac Sci, Orumiyeh, Iran
来源：
MICROCHIMICA ACTA | 2017年 / 184卷 / 02期
关键词：
Immunosensing; Tumor biomarker; Nanotechnology; Biotechnology; Microfluidics; Multiplex sensor; Electroanalysis; Electrochemical biosensing; Nanoparticles; Upconversion nanoparticles; Graphene; Graphene quantumdots; Hyperbranched polymers; GLASSY-CARBON ELECTRODE; CORE-SHELL NANOPARTICLES; SIGNAL AMPLIFICATION STRATEGY; SILICA-BASED MATERIALS; GOLD NANOPARTICLES; LABEL-FREE; GRAPHENE OXIDE; AMPEROMETRIC IMMUNOSENSOR; FUNCTIONALIZED GRAPHENE; HORSERADISH-PEROXIDASE;
D O I：
10.1007/s00604-016-2066-2
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
This review (with 196 refs.) covers the state of the art in electrochemical and optical immunoassays for the carcinoembryonic antigen (CEA). In essence, it has sections on (a) frequently applied principles and types of CEA immunoassays; (b) aspects of sensor fabrication including immunological and immobilization procedures and the proper choice of nanomaterials; (c) electrochemical immunoassays, with subsections on assays based on the use of nanoparticles and other nanomaterials (such as conducting polymers and graphenes); (d) optical immunoassays based on the use of nanoparticles such as quantum dots, gold nanoparticles, upconversion nanoparticles, graphenes and their derivatives; (d) lateral flow and lab-on-a-chip (microfluidic) immunoassays; and (e) on multiplexed electrochemical and optical immunoassays with and without labels. Examples for applications to real samples are given. A final section discusses current limitations and trends in terms of sensing schemes and nanomaterials.
引用
收藏
页码：389 / 414
页数：26
相关论文
共 169 条
[71]   Impedance sensing of DNA binding drugs using gold substrates modified with gold nanoparticles [J].
Li, CZ ;
Liu, YL ;
Luong, JHT .
ANALYTICAL CHEMISTRY, 2005, 77 (02) :478-485
[72]   Electrochemical Biosensor Based on Nanocomposites Film of Thiol Graphene-Thiol Chitosan/Nano Gold for the Detection of Carcinoembryonic Antigen [J].
Li, Guobao ;
Xue, Qi ;
Feng, Jijun ;
Sui, Weiping .
ELECTROANALYSIS, 2015, 27 (05) :1245-1252
[73]   Synthesis of Mn3O4-anchored graphene sheet nanocomposites via a facile, fast microwave hydrothermal method and their supercapacitive behavior [J].
Li, Li ;
Seng, Kuok Hau ;
Chen, Zhixin ;
Liu, Huakun ;
Nevirkovets, Ivan P. ;
Guo, Zaiping .
ELECTROCHIMICA ACTA, 2013, 87 :801-808
[74]   TEA-assisted synthesis of single-crystalline Mn3O4 octahedrons and their magnetic properties [J].
Li, Li ;
Liang, Jun ;
Kang, Hui ;
Fang, Junzhuo ;
Luo, Min ;
Jin, Xiaoyong .
APPLIED SURFACE SCIENCE, 2012, 261 :717-721
[75]   Simultaneous detection of two tumor markers using silver and gold nanoparticles decorated carbon nanospheres as labels [J].
Li, Lihua ;
Feng, Dexiang ;
Zhang, Yuzhong .
ANALYTICAL BIOCHEMISTRY, 2016, 505 :59-65
[76]   Three-Dimensional Hierarchical Plasmonic Nano-Architecture Enhanced Surface-Enhanced Raman Scattering Immunosensor for Cancer Biomarker Detection in Blood Plasma [J].
Li, Ming ;
Cushing, Scott K. ;
Zhang, Jianming ;
Suri, Savan ;
Evans, Rebecca ;
Petros, William P. ;
Gibson, Laura F. ;
Ma, Dongling ;
Liu, Yuxin ;
Wu, Nianqiang .
ACS NANO, 2013, 7 (06) :4967-4976
[77]   Novel graphene-gold nanohybrid with excellent electrocatalytic performance for the electrochemical detection of glucose [J].
Li Ruiyi ;
Zhang Juanjuan ;
Wang Zhouping ;
Li Zaijun ;
Liu Junkang ;
Gu Zhiguo ;
Wang Guangli .
SENSORS AND ACTUATORS B-CHEMICAL, 2015, 208 :421-428
[78]   Graphene Oxide as a Quencher for Fluorescent Assay of Amino Acids, Peptides, and Proteins [J].
Li, Shanghao ;
Aphale, Ashish N. ;
Macwan, Isaac G. ;
Patra, Prabir K. ;
Gonzalez, Walter G. ;
Miksovska, Jaroslava ;
Leblanc, Roger M. .
ACS APPLIED MATERIALS & INTERFACES, 2012, 4 (12) :7068-7074
[79]   Electrochemical Immunosensor for Carcinoembryonic Antigen Detection Based on Mo-Mn3O4/MWCNTs/Chits Nanocomposite Modified ITO Electrode [J].
Li, Wen-Ting ;
Wang, Yu ;
Deng, Fen-Fang ;
Liu, Li-Li ;
Nan, Hai-Jun ;
Li, He .
NANO, 2015, 10 (08)
[80]   A Sensitive Label-free Amperometric CEA Immunosensor Based on Graphene-Nafion Nanocomposite Film as an Enhanced Sensing Platform [J].
Li, Yan ;
Yang, Wei-Kang ;
Fan, Man-Qi ;
Liu, Ao .
ANALYTICAL SCIENCES, 2011, 27 (07) :727-731
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