Drivers of and Barriers to COVID-19 Vaccine Booster Dose Acceptance in Indonesia

被引：5

作者：

Harapan, Harapan ^{[1
,2
,3
,4
]}

Fathima, Raisha ^{[1
]}

Kusuma, Hendrix Indra ^{[1
,5
,6
]}

Anwar, Samsul ^{[7
]}

Nalapraya, Widhy Yudistira ^{[8
]}

Wibowo, Adityo ^{[9
]}

Wati, Ketut Dewi Kumara ^{[10
]}

Medina, Ayunda ^{[1
]}

Defrita, Anna Hanifa ^{[11
]}

Astri, Yesi ^{[12
]}

Prasetyowati, Arie ^{[13
]}

Nurfarahin, Nurfarahin ^{[1
]}

Khusna, Afriyani ^{[1
]}

Oktariana, Setya ^{[1
]}

Anwar, Sarifuddin ^{[14
]}

Yussar, Milza Oka ^{[15
]}

Khotimah, Siti ^{[16
]}

Nainggolan, Bahagia Willibrordus Maria ^{[17
]}

Badri, Putri Rizki Amalia ^{[18
]}

Argarini, Raden ^{[19
]}

Winardi, Wira ^{[20
]}

Indah, Rosaria ^{[21
]}

Sallam, Malik ^{[22
,23
,24
]}

Rajamoorthy, Yogambigai ^{[25
]}

Wagner, Abram L. ^{[26
]}

Mudatsir, Mudatsir ^{[1
,2
,3
]}

机构：

[1] Univ Syiah Kuala, Sch Med, Med Res Unit, Banda Aceh 23111, Indonesia

[2] Univ Syiah Kuala, Trop Dis Ctr, Sch Med, Banda Aceh 23111, Indonesia

[3] Univ Syiah Kuala, Sch Med, Dept Microbiol, Banda Aceh 23111, Indonesia

[4] Univ Syiah Kuala, Tsunami & Disaster Mitigat Res Ctr TDMRC, Banda Aceh 23111, Indonesia

[5] Univ Syiah Kuala, Fac Math & Nat Sci, Dept Biol, Banda Aceh 23111, Indonesia

[6] Univ Islam Negeri Ar Raniry, Fac Tarbiyah & Teacher Training, Biol Educ Dept, Banda Aceh 23111, Indonesia

[7] Univ Syiah Kuala, Fac Math & Nat Sci, Dept Stat, Banda Aceh 23111, Indonesia

[8] Univ Islam Bandung, Fac Med, Dept Pulmonol & Resp Med, Bandung 40116, Indonesia

[9] Univ Lampung, Fac Med, Dept Pulmonol & Resp Med, Bandar Lampung 35145, Indonesia

[10] Univ Udayana, Fac Med, Dept Child Hlth, Denpasar 80234, Indonesia

[11] Univ Jambi, Fac Med, Jambi 36373, Indonesia

[12] Univ Muhammadiyah Palembang, Fac Med, Neurol Dept, Palembang 30263, Indonesia

[13] Mungkid Community Hlth Ctr, Magelang 56512, Indonesia

[14] Tadulako Univ, Fac Med, Dept Pulmonol & Resp Med, Palu 94148, Indonesia

[15] Univ Muhammadiyah Aceh, Fac Publ Hlth, Banda Aceh 23245, Indonesia

[16] Mulawarman Univ, Biochem Lab, Med Fac, Samarinda 75119, Indonesia

[17] Univ Sumatera Utara, Fac Med, Undergrad Program Med, Medan 20155, Indonesia

[18] Univ Muhammadiyah Palembang, Fac Med, Publ Hlth Dept, Palembang 30263, Indonesia

[19] Univ Airlangga, Dept Med Physiol & Biochem, Surabaya 60132, Indonesia

[20] Univ Syiah Kuala, Sch Med, Dept Pulmonol & Resp Med, Banda Aceh 23111, Indonesia

[21] Univ Syiah Kuala, Sch Med, Med Educ Unit, Banda Aceh 23111, Indonesia

[22] Univ Jordan, Sch Med, Dept Pathol Microbiol & Forens Med, Amman 11942, Jordan

[23] Jordan Univ Hosp, Dept Clin Labs & Forens Med, Amman 11942, Jordan

[24] Lund Univ, Fac Med, Dept Translat Med, S-22184 Malmo, Sweden

[25] Univ Tunku Abdul Rahman, Fac Accountancy & Management, Dept Econ, Kuala Lumpur 43200, Malaysia

[26] Univ Michigan, Sch Publ Hlth, Dept Epidemiol, Ann Arbor, MI 48109 USA

来源：

VACCINES | 2022年 / 10卷 / 12期

关键词：

booster dose; vaccine acceptance; vaccine reluctance; COVID-19; vaccine resistance; vaccine rejection; vaccine hesitancy;

D O I：

10.3390/vaccines10121981

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Obtaining a booster dose of coronavirus disease 2019 (COVID-19) vaccine is required to maintain the protective level of neutralizing antibodies and therefore herd immunity in the community, and the success of booster dose programs depends on public acceptance. The aim of this study was to determine the acceptance of a booster dose of COVID-19 vaccine and its drivers and barriers in Indonesia. A cross-sectional survey was conducted in the provinces of Indonesia between 1 and 15 August 2022. Individuals who completed the primary series of the COVID-19 vaccine were asked about their acceptance of a booster dose. Those who refused the booster dose were questioned about their reasons. A logistic regression was used to determine the determinants associated with rejection of a booster dose of COVID-19 vaccine. A total of 2935 respondents were included in the final analysis. With no information on the efficacy and safety of the COVID-19 vaccine, 95% of respondents agreed to receive a booster dose if it were provided for free by the government. This acceptance was reduced to only 50.3% if the vaccine had a 75% efficacy with a 20% chance of side effects. The adjusted logistic regression analysis indicated that there were eight factors associated with the rejection of the booster dose: age, marital status, religion, occupation, type of the first two vaccines received, knowledge regarding the importance of the booster dose, belief that natural immunity is sufficient to prevent COVID-19 and disbelief in the effectiveness of the booster dose. In conclusion, the hesitancy toward booster doses in Indonesia is influenced by some intrinsic factors such as lack of knowledge on the benefits of the booster dose, worries regarding the unexpected side effects and concerns about the halal status of the provided vaccines and extrinsic determinants such as the effectiveness and safety of the vaccine. These findings suggest the need for more campaigns and promotions regarding the booster dose benefits to increase its acceptance.

引用

页数：20

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