Impact of epidural bupivacaine on perioperative opioid requirements, recovery characteristics, and duration of hospitalization in dogs undergoing cystotomy: A retrospective study of 56 cases

被引:8
作者
Floriano, Dario [1 ]
Sahagian, Michael J. [1 ]
Chiavaccini, Ludovica [2 ]
机构
[1] Univ Penn, Matthew J Ryan Vet Hosp, Dept Clin Studies, Philadelphia, PA 19104 USA
[2] North Carolina State Univ, Dept Mol & Biomed Sci, Raleigh, NC 27695 USA
关键词
POSTOPERATIVE URINARY RETENTION; ANESTHESIA; SURGERY; ANALGESIA; MORPHINE; PREVALENCE; MANAGEMENT; MORTALITY; FENTANYL; PAIN;
D O I
10.1111/vsu.13290
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
Objective To compare perioperative opioid consumption and duration of hospitalization (DOH) in anesthetized dogs receiving opioid-based analgesia (OBA) vs those receiving bupivacaine epidural-based analgesia (EPID) during cystotomy. Study design Retrospective cross-sectional study. Animals Fifty-six client-owned dogs undergoing cystotomy. Methods Clinical records of dogs undergoing cystotomy between January 2015 and December 2017 were reviewed. Demographic data, duration of anesthesia and surgery, anesthetic management, perioperative opioid consumption expressed in morphine equivalents (ME), perioperative use of adjuvant analgesics, time to first micturition, time to eat, time to ambulate, and DOH were recorded. Opioid consumption and DOH were compared with a Wilcoxon rank-sum test, followed by linear regression analysis as appropriate. Time to first micturition, time to eat, and time to walk unassisted were modeled with Cox-proportional hazard models. Results Dogs treated with EPID during surgery required 1.5 mg/kg ME less compared with those treated with OBA (P = .04) during surgery. Three of 19 dogs treated with EPID vs 15 of 37 dogs receiving OBA required intraoperative adjuvant analgesics (P = .06). Dogs treated with EPID regained motor function slower than dogs treated with OBA (P = .01); however, there was no difference in time to urinate, time to eat, or DOH between treatments. Conclusion Perioperative lumbosacral epidural with bupivacaine reduced intraoperative opioid consumption in dogs anesthetized for cystotomy. Clinical significance The use of epidural bupivacaine in dogs undergoing cystotomy may reduce intraoperative opioid requirements without affecting return of bladder function or DOH.
引用
收藏
页码:1330 / 1337
页数:8
相关论文
共 34 条
  • [1] Evaluation of costs and time required for laparoscopic-assisted versus open cystotomy for urinary cystolith removal in dogs: 43 cases (2009-2012)
    Arulpragasam, Shiara P.
    Case, J. Brad
    Ellison, Gary W.
    [J]. JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 2013, 243 (05): : 703 - 708
  • [2] Postoperative Urinary Retention Anesthetic and Perioperative Considerations
    Baldini, Gabriele
    Bagry, Hema
    Aprikian, Armen
    Carli, Franco
    [J]. ANESTHESIOLOGY, 2009, 110 (05) : 1139 - 1157
  • [3] Neuraxial anesthesia versus general anesthesia for urological surgery: systematic review
    Barbosa, Fabiano Timbo
    Castro, Aldemar Araujo
    [J]. SAO PAULO MEDICAL JOURNAL, 2013, 131 (03): : 179 - 186
  • [4] Prevalence of Dysphoria after Fentanyl in Dogs Undergoing Stifle Surgery
    Becker, Willem M.
    Mama, Khursheed R.
    Rao, Sangeeta
    Palmer, Ross H.
    Egger, Erick L.
    [J]. VETERINARY SURGERY, 2013, 42 (03) : 302 - 307
  • [5] Biswai A V, 1976, Can Anaesth Soc J, V23, P296
  • [6] EMETIC AND ANTIEMETIC EFFECTS OF OPIOIDS IN THE DOG
    BLANCQUAERT, JP
    LEFEBVRE, RA
    WILLEMS, JL
    [J]. EUROPEAN JOURNAL OF PHARMACOLOGY, 1986, 128 (03) : 143 - 150
  • [7] CHANGES IN MICTURITION VOLUME THRESHOLDS IN CONSCIOUS DOGS FOLLOWING SPINAL OPIATE ADMINISTRATION
    BOLAM, JM
    ROBINSON, CJ
    HOFSTRA, TC
    WURSTER, RD
    [J]. JOURNAL OF THE AUTONOMIC NERVOUS SYSTEM, 1986, 16 (04): : 261 - 277
  • [8] FEEDING BEHAVIOUR OF ADULT DOGS UNDER CONDITIONS OF HOSPITALIZATION
    BOULCOTT, SR
    [J]. BRITISH VETERINARY JOURNAL, 1967, 123 (11): : 498 - &
  • [9] Comparison of the effects of epidural or intravenous methadone on the minimum alveolar concentration of isoflurane in dogs
    Campagnol, Daniela
    Teixeira-Neto, Francisco J.
    Peccinini, Rosangela G.
    Oliveira, Flavia A.
    Alvaides, Renata K.
    Medeiros, Luiza Q.
    [J]. VETERINARY JOURNAL, 2012, 192 (03) : 311 - 315
  • [10] Comparison of bupivacaine femoral and sciatic nerve block versus bupivacaine and morphine epidural for stifle surgery in dogs
    Campoy, Luis
    Martin-Flores, Manuel
    Ludders, John W.
    Erb, Hollis N.
    Gleed, Robin D.
    [J]. VETERINARY ANAESTHESIA AND ANALGESIA, 2012, 39 (01) : 91 - 98