Microrheology

被引：303
作者：
MacKintosh, FC [1 ]
Schmidt, CF
机构：
[1] Univ Michigan, Randall Lab, Dept Phys & Biophys, Div Res, Ann Arbor, MI 48109 USA
[2] Free Univ Amsterdam, FEW, Div Phys & Astron, Dept Biophys, NL-1081 HV Amsterdam, Netherlands
来源：
CURRENT OPINION IN COLLOID & INTERFACE SCIENCE | 1999年 / 4卷 / 04期
关键词：
rheology; viscoelasticity; biopolymers; atomic force microscopy (AFM); cell mechanics;
D O I：
10.1016/S1359-0294(99)90010-9
中图分类号：
O64 [物理化学（理论化学）、化学物理学];
学科分类号：
070304 ; 081704 ;
摘要：
Several complementary techniques have been developed in recent years that make it possible to measure viscoelastic properties of soft materials on micrometer scales. Such methods provide new prospects for the characterization of local inhomogeneities in materials, for studies of material properties in small samples, including living cells, and for high frequency rheology. The main techniques discussed in this review are magnetic bead manipulation, observation of refractive beads with laser interferometry or multiply scattered light, and atomic force microscopy. Materials studied include synthetic polymers, thin polymer films, biological polymers in vitro and in vivo. (C) 1999 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：300 / 307
页数：8
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