Fluorene-based chemodosimeter for "turn-on" sensing of cyanide by hampering ESIPT and live cell imaging

被引：56

作者：

Bera, Manas Kumar ^{[1
]}

Chakraborty, Chanchal ^{[1
]}

Singh, Pradeep Kumar ^{[2
]}

Sahu, Chandan ^{[3
]}

Sen, Kaushik ^{[3
]}

Maji, Samir ^{[2
]}

Das, Abhijit Kumar ^{[3
]}

Malik, Sudip ^{[1
]}

机构：

[1] Indian Assoc Cultivat Sci, Polymer Sci Unit, Kolkata 700032, India

[2] Indian Assoc Cultivat Sci, Dept Spect, Kolkata 700032, India

[3] Indian Inst Technol, Dept Biosci & Bioengn, Bombay 400076, Maharashtra, India

来源：

JOURNAL OF MATERIALS CHEMISTRY B | 2014年 / 2卷 / 29期

关键词：

ANION RECOGNITION; SELECTIVE RECOGNITION; SODIUM-CYANIDE; SENSOR; RECEPTORS; MOLECULES; MECHANISM; DENSITY; ION;

D O I：

10.1039/c4tb00388h

中图分类号：

TB3 [工程材料学]; R318.08 [生物材料学];

学科分类号：

0805 ; 080501 ; 080502 ;

摘要：

A new salicylaldehyde appended fluorene-based chemodosimeter (FSal) has been designed by taking consideration of the special nucleophilicity of cyanide ion. FSal shows selective affinity towards CN- over other anions (namely F-, Br-, NO3-, ClO4-, N-3(-), H2PO4-, AcO-, I-, Cl-, and NO2-) through turn-on fluorescence with a minimum detection limit of 0.06 ppm. The turn-on fluorescence of the FSal-CN complex resulting from hampering ESIPT is also supported by DFT and TDDFT calculations. Biological compatibility and live cell imaging of this unique probe have also been explored.

引用

页码：4733 / 4739

页数：7

共 47 条

[1]

[Anonymous], 2001, ANGEW CHEM

[2] Luminescence lifetime-based sensor for cyanide and related anions [J].

Anzenbacher, P ;

Tyson, DS ;

Jursíková, K ;

Castellano, FN .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2002, 124 (22) :6232-6233

[3] Enhanced fluorescence cyanide detection at physiologically lethal levels: Reduced ICT-based signal transduction [J].

Badugu, R ;

Lakowicz, JR ;

Geddes, CD .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2005, 127 (10) :3635-3641

[4]

Baskin S.I., 1997, TXB MILITARY MED MED, P271

[5] Cyanide: critical issues in diagnosis and treatment [J].

Baud, F. J. .

HUMAN & EXPERIMENTAL TOXICOLOGY, 2007, 26 (03) :191-201

[6] DENSITY-FUNCTIONAL EXCHANGE-ENERGY APPROXIMATION WITH CORRECT ASYMPTOTIC-BEHAVIOR [J].

BECKE, AD .

PHYSICAL REVIEW A, 1988, 38 (06) :3098-3100

[7] Transition-metal receptor systems for the selective recognition and sensing of anionic guest species [J].

Beer, PD .

ACCOUNTS OF CHEMICAL RESEARCH, 1998, 31 (02) :71-80

[8]

Beer PD, 2001, ANGEW CHEM INT EDIT, V40, P486, DOI 10.1002/1521-3773(20010202)40:3<486::AID-ANIE486>3.0.CO

[9]

2-P

[10] Conjugated Polyfluorene-based Reversible Fluorescent Sensor for Cu(II) and Cyanide Ions in Aqueous Medium [J].

Chakraborty, Chanchal ;

Singh, Pradeep ;

Maji, Samir K. ;

Malik, Sudip .

CHEMISTRY LETTERS, 2013, 42 (11) :1355-1357

← 1 2 3 4 5 →