FRAGMENTATION AND AGGREGATION OF PHYSIOLOGICAL AND PARKINSON-SYNUCLEINS REVEALED BY ION MOBILITY AND AFFINITY-MASS SPECTROMETRY

被引：0

作者：

Przybylski, M. ^{[1
,2
]}

Slamnoiu, S. ^{[1
,2
]}

Stumbaum, M. ^{[1
,2
]}

Vlad, C. ^{[1
,2
]}

Lindner, K. ^{[1
,2
]}

Karreman, C. ^{[1
,2
]}

Kipping, M. ^{[3
]}

Desor, M. ^{[3
]}

Leist, M.

Hengerer, B. ^{[4
]}

机构：

[1] Univ Konstanz, Lab Analyt Chem & Biopolymer Struct Anal, Dept Chem, Constance, Germany

[2] Univ Konstanz, Lab Analyt Chem & Biopolymer Struct Anal, Dept Biol, Constance, Germany

[3] Waters GmbH, Eschborn, Germany

[4] Boehringer Ingelheim Pharma GmbH & Co KG, ZNS Res Dept, Biberach, Germany

来源：

JOURNAL OF PEPTIDE SCIENCE | 2014年 / 20卷

关键词：

Physiological and Parkinson synucleins; Fragmentation- aggregation pathways; ion mobility- mass spectrometry; aggregation-prone sequence mutation;

D O I：

暂无

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

O53

引用

页码：S71 / S71

页数：1

共 2 条

[1] On-Line Bioaffinity-Electrospray Mass Spectrometry for Simultaneous Detection, Identification, and Quantification of Protein-Ligand Interactions [J].

Dragusanu, Mihaela ;

Petre, Brindusa-Alina ;

Slamnoiu, Stefan ;

Vlad, Camelia ;

Tu, Tingting ;

Przybylski, Michael .

JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 2010, 21 (10) :1643-1648

[2] Autoproteolytic Fragments Are Intermediates in the Oligomerization/Aggregation of the Parkinson's Disease Protein Alpha-Synuclein as Revealed by Ion Mobility Mass Spectrometry [J].

Vlad, Camelia ;

Lindner, Kathrin ;

Karreman, Christiaan ;

Schildknecht, Stefan ;

Leist, Marcel ;

Tomczyk, Nick ;

Rontree, John ;

Langridge, James ;

Danzer, Karin ;

Ciossek, Thomas ;

Petre, Alina ;

Gross, Michael L. ;

Hengerer, Bastian ;

Przybylski, Michael .

CHEMBIOCHEM, 2011, 12 (18) :2740-2744

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