Brain development and the genetics of brain development

被引：16
作者：
Clark, GD
机构：
[1] Cain Fdn Labs, Dept Pediat, Houston, TX 77030 USA
[2] Cain Fdn Labs, Dept Neurol, Houston, TX 77030 USA
[3] Cain Fdn Labs, Dept Neurosci, Houston, TX 77030 USA
来源：
NEUROLOGIC CLINICS | 2002年 / 20卷 / 04期
关键词：
D O I：
10.1016/S0733-8619(02)00024-5
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
The human brain is the most complex of organs that nature has yet provided. The formation of the human brain has been studied extensively, but the brain is only now yielding its genetic secrets. In this article the author reviews the formation of human brain and the disorders that result from disturbances in this development. Where possible, the genetic disruption believed to be responsible for the malformation are detailed, the developmental process that is disturbed is reviewed, the typical clinical features are described, and the genetic consequences to the child and family is discussed.
引用
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页码：917 / +
页数：24
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