Daily Caffeine Consumption Does Not Influence Acupuncture Analgesia in Healthy Individuals: A Preliminary Study

被引:4
作者
Cao, Jin [1 ]
Tu, Yiheng [1 ]
Lang, Courtney [1 ]
Vangel, Mark [2 ]
Park, Joel [1 ]
Liu, Jiao [1 ]
Wilson, Georgia [1 ]
Gollub, Randy [1 ,3 ]
Orr, Scott [1 ]
Kong, Jian [1 ,3 ]
机构
[1] Harvard Med Sch, Massachusetts Gen Hosp, Dept Psychiat, Bldg 120,Room 101 C, Charlestown, MA 02129 USA
[2] Harvard Med Sch, Massachusetts Gen Hosp, Dept Med, Charlestown, MA 02129 USA
[3] Harvard Med Sch, Massachusetts Gen Hosp, Athinoula A Marti Nos Ctr Biomed Imaging, Charlestown, MA 02129 USA
基金
美国国家卫生研究院;
关键词
D O I
10.1213/ANE.0000000000003989
中图分类号
R614 [麻醉学];
学科分类号
100217 ;
摘要
Animal studies suggest that caffeine may interfere with acupuncture analgesia. This study investigated the modulation effect of daily caffeine intake on acupuncture analgesia in 27 healthy subjects using a crossover design. We found that real acupuncture increased pain thresholds compared to sham acupuncture. Further, there was no association between caffeine intake measurements of daily caffeine use, duration of caffeine consumption, or their interaction and preacupuncture and postacupuncture pain threshold changes. Our findings suggest that daily caffeine intake may not influence acupuncture analgesia in the cohort of healthy subjects who participated in study.
引用
收藏
页码:E6 / E9
页数:4
相关论文
共 15 条
[1]  
Angst MS, 2009, J VIS EXP, P1092
[2]  
[Anonymous], CONSUMERS GUIDE PSYC
[3]   Analgesic Effects Evoked by Real and Imagined Acupuncture: A Neuroimaging Study [J].
Cao, Jin ;
Tu, Yiheng ;
Orr, Scott P. ;
Lang, Courtney ;
Park, Joel ;
Vangel, Mark ;
Chen, Lucy ;
Gollub, Randy ;
Kong, Jian .
CEREBRAL CORTEX, 2019, 29 (08) :3220-3231
[4]   Thermal and Pressure Pain Sensitivity in Patients With Unilateral Shoulder Pain: Comparison of Involved and Uninvolved Sides [J].
Coronado, Rogelio A. ;
Kindler, Lindsay L. ;
Valencia, Carolina ;
George, Steven Z. .
JOURNAL OF ORTHOPAEDIC & SPORTS PHYSICAL THERAPY, 2011, 41 (03) :165-173
[5]   A combined [11C]diprenorphine PET study and fMRI study of acupuncture analgesia [J].
Dougherty, Darin D. ;
Kong, Jian ;
Webb, Megan ;
Bonab, Ali A. ;
Fischman, Alan J. ;
Gollub, Randy L. .
BEHAVIOURAL BRAIN RESEARCH, 2008, 193 (01) :63-68
[6]   Presence of caffeine reversibly interferes with efficacy of acupuncture-induced analgesia [J].
Fujita, Takumi ;
Feng, Changyong ;
Takano, Takahiro .
SCIENTIFIC REPORTS, 2017, 7
[7]   Caffeine-Not just a stimulant [J].
Glade, Michael J. .
NUTRITION, 2010, 26 (10) :932-938
[8]   Adenosine A1 receptors mediate local anti-nociceptive effects of acupuncture [J].
Goldman, Nanna ;
Chen, Michael ;
Fujita, Takumi ;
Xu, Qiwu ;
Peng, Weiguo ;
Liu, Wei ;
Jensen, Tina K. ;
Pei, Yong ;
Wang, Fushun ;
Han, Xiaoning ;
Chen, Jiang-Fan ;
Schnermann, Jurgen ;
Takano, Takahiro ;
Bekar, Lane ;
Tieu, Kim ;
Nedergaard, Maiken .
NATURE NEUROSCIENCE, 2010, 13 (07) :883-U130
[9]   Acupuncture analgesia: Areas of consensus and controversy [J].
Han, Ji-Sheng .
PAIN, 2011, 152 (03) :S41-S48
[10]   Brain activity associated with expectancy-enhanced placebo analgesia as measured by functional magnetic resonance Imaging [J].
Kong, J ;
Gollub, RL ;
Rosman, IS ;
Webb, JM ;
Vangel, MG ;
Kirsch, I ;
Kaptchuk, TJ .
JOURNAL OF NEUROSCIENCE, 2006, 26 (02) :381-388