THE IMPORTANCE OF CHEMOTHERAPY IN THE MANAGEMENT STRATEGIES REGARDING HEPATIC METASTASES IN COLORECTAL CANCER
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Ginghina, Octav
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Carol Davila Univ Med & Pharm, Sf Joan Hosp, Fac Med Dent, Dept Surg Oncol, Bucharest 042122, RomaniaCarol Davila Univ Med & Pharm, Sf Joan Hosp, Fac Med Dent, Dept Surg Oncol, Bucharest 042122, Romania
Ginghina, Octav
[1
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Dragomiroiu, George Traian Alexandru Burcea
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Carol Davila Univ Med & Pharm, Fac Pharm, Dept Drug Control, Bucharest 020956, RomaniaCarol Davila Univ Med & Pharm, Sf Joan Hosp, Fac Med Dent, Dept Surg Oncol, Bucharest 042122, Romania
Dragomiroiu, George Traian Alexandru Burcea
[2
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Negrei, Carolina
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Carol Davila Univ Med & Pharm, Fac Pharm, Dept Toxicol, Bucharest 020956, RomaniaCarol Davila Univ Med & Pharm, Sf Joan Hosp, Fac Med Dent, Dept Surg Oncol, Bucharest 042122, Romania
Negrei, Carolina
[3
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Barca, Maria
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Carol Davila Univ Med & Pharm, Fac Pharm, Dept Drug Control, Bucharest 020956, RomaniaCarol Davila Univ Med & Pharm, Sf Joan Hosp, Fac Med Dent, Dept Surg Oncol, Bucharest 042122, Romania
Barca, Maria
[2
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机构:
[1] Carol Davila Univ Med & Pharm, Sf Joan Hosp, Fac Med Dent, Dept Surg Oncol, Bucharest 042122, Romania
[2] Carol Davila Univ Med & Pharm, Fac Pharm, Dept Drug Control, Bucharest 020956, Romania
[3] Carol Davila Univ Med & Pharm, Fac Pharm, Dept Toxicol, Bucharest 020956, Romania
The liver is the most common site for haematogenous metastases in colorectal cancer. Over the past ten years the survival rate in patients with hepatic metastases has significantly improved, mostly because of the development of new chemotherapy protocols, as well as new therapeutic agents. Overall, these are strengthening the effects of surgery, which in case of radical resection offers the best survival. Moreover, surgical control of liver metastatic extensive disease can combine resection with ablation therapies or staged methods. Today, the treatment of colorectal cancer liver metastases is essentially multidisciplinary, the medical oncologist together with the surgeon and the gastro-enterologist deciding the therapeutical sequence individualised for each patient.
机构:
Department of Oncology, McGill University, Montreal, Que.
Department of Oncology, McGill University, McIntyre Medical Sciences Building, MontrealDepartment of Oncology, McGill University, Montreal, Que.
Leyland-Jones B.
Burdette-Radoux S.
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Department of Oncology, McGill University, Montreal, Que.Department of Oncology, McGill University, Montreal, Que.
机构:
Univ Bologna, S Orsola M Malpighi Hosp, Liver & Multiorgan Transplant Unit, I-40138 Bologna, ItalyUniv Bologna, S Orsola M Malpighi Hosp, Liver & Multiorgan Transplant Unit, I-40138 Bologna, Italy
Cucchetti, Alessandro
Ercolani, Giorgio
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Univ Bologna, S Orsola M Malpighi Hosp, Liver & Multiorgan Transplant Unit, I-40138 Bologna, ItalyUniv Bologna, S Orsola M Malpighi Hosp, Liver & Multiorgan Transplant Unit, I-40138 Bologna, Italy
Ercolani, Giorgio
Cescon, Matteo
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Univ Bologna, S Orsola M Malpighi Hosp, Liver & Multiorgan Transplant Unit, I-40138 Bologna, ItalyUniv Bologna, S Orsola M Malpighi Hosp, Liver & Multiorgan Transplant Unit, I-40138 Bologna, Italy
Cescon, Matteo
Di Gioia, Paolo
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Univ Bologna, S Orsola M Malpighi Hosp, Liver & Multiorgan Transplant Unit, I-40138 Bologna, ItalyUniv Bologna, S Orsola M Malpighi Hosp, Liver & Multiorgan Transplant Unit, I-40138 Bologna, Italy
Di Gioia, Paolo
Peri, Eugenia
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Univ Bologna, S Orsola M Malpighi Hosp, Liver & Multiorgan Transplant Unit, I-40138 Bologna, ItalyUniv Bologna, S Orsola M Malpighi Hosp, Liver & Multiorgan Transplant Unit, I-40138 Bologna, Italy
Peri, Eugenia
Brandi, Giovanni
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Univ Bologna, Dept Hematol & Oncol Sci, I-40138 Bologna, ItalyUniv Bologna, S Orsola M Malpighi Hosp, Liver & Multiorgan Transplant Unit, I-40138 Bologna, Italy
Brandi, Giovanni
Pellegrini, Sara
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Univ Bologna, S Orsola M Malpighi Hosp, Liver & Multiorgan Transplant Unit, I-40138 Bologna, ItalyUniv Bologna, S Orsola M Malpighi Hosp, Liver & Multiorgan Transplant Unit, I-40138 Bologna, Italy
Pellegrini, Sara
Pinna, Antonio Daniele
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Univ Bologna, S Orsola M Malpighi Hosp, Liver & Multiorgan Transplant Unit, I-40138 Bologna, ItalyUniv Bologna, S Orsola M Malpighi Hosp, Liver & Multiorgan Transplant Unit, I-40138 Bologna, Italy
机构:
Mem Sloan Kettering Canc Ctr, New York, NY 10021 USA
Cornell Univ, Weill Med Coll, Ithaca, NY 14853 USAMem Sloan Kettering Canc Ctr, New York, NY 10021 USA
Kemeny, Nancy
JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK,
2010,
8
(05):
: 507
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509
机构:
Yokohama City Univ, Grad Sch Med, Dept Surg Gastroenterol, Kanazawa Ku, Yokohama, Kanagawa 2360004, JapanYokohama City Univ, Grad Sch Med, Dept Surg Gastroenterol, Kanazawa Ku, Yokohama, Kanagawa 2360004, Japan
Tanaka, Kuniya
Takakura, Hideki
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Yokohama City Univ, Grad Sch Med, Dept Surg Gastroenterol, Kanazawa Ku, Yokohama, Kanagawa 2360004, JapanYokohama City Univ, Grad Sch Med, Dept Surg Gastroenterol, Kanazawa Ku, Yokohama, Kanagawa 2360004, Japan
Takakura, Hideki
Takeda, Kazuhisa
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Yokohama City Univ, Grad Sch Med, Dept Surg Gastroenterol, Kanazawa Ku, Yokohama, Kanagawa 2360004, JapanYokohama City Univ, Grad Sch Med, Dept Surg Gastroenterol, Kanazawa Ku, Yokohama, Kanagawa 2360004, Japan
Takeda, Kazuhisa
Matsuo, Kenichi
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Yokohama City Univ, Grad Sch Med, Dept Surg Gastroenterol, Kanazawa Ku, Yokohama, Kanagawa 2360004, JapanYokohama City Univ, Grad Sch Med, Dept Surg Gastroenterol, Kanazawa Ku, Yokohama, Kanagawa 2360004, Japan
Matsuo, Kenichi
Nagano, Yasuhiko
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Yokohama City Univ, Grad Sch Med, Dept Surg Gastroenterol, Kanazawa Ku, Yokohama, Kanagawa 2360004, JapanYokohama City Univ, Grad Sch Med, Dept Surg Gastroenterol, Kanazawa Ku, Yokohama, Kanagawa 2360004, Japan
机构:
Univ Tokyo, Hepatobiliary Pancreat Surg Div, Dept Surg, Grad Sch Med,Bunkyo Ku, Tokyo 1138655, JapanUniv Tokyo, Hepatobiliary Pancreat Surg Div, Dept Surg, Grad Sch Med,Bunkyo Ku, Tokyo 1138655, Japan
Takahashi, Michiro
Ohba, Masaru
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Univ Tokyo, Hepatobiliary Pancreat Surg Div, Dept Surg, Grad Sch Med,Bunkyo Ku, Tokyo 1138655, JapanUniv Tokyo, Hepatobiliary Pancreat Surg Div, Dept Surg, Grad Sch Med,Bunkyo Ku, Tokyo 1138655, Japan
Ohba, Masaru
Kaneko, Junichi
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Univ Tokyo, Hepatobiliary Pancreat Surg Div, Dept Surg, Grad Sch Med,Bunkyo Ku, Tokyo 1138655, JapanUniv Tokyo, Hepatobiliary Pancreat Surg Div, Dept Surg, Grad Sch Med,Bunkyo Ku, Tokyo 1138655, Japan