MATERNALLY DERIVED ANTIBODIES AGAINST BORDETELLA PERTUSSIS ANTIGENS PERTUSSIS TOXIN AND FILAMENTOUS HEMAGGLUTININ IN PRETERM AND FULL TERM NEWBORNS

被引：40

作者：

Heininger, Ulrich ^{[1
]}

Riffelmann, Marion ^{[2
,3
]}

Leineweber, Birgit ^{[1
]}

von Koenig, Carl Heinz Wirsing ^{[2
,3
]}

机构：

[1] Univ Childrens Hosp, Div Pediat Infect Dis, CH-4005 Basel, Switzerland

[2] Krefeld GmbH, Inst Infektiol, Krefeld, Germany

[3] HELIOS Klinikum Krefeld, Krefeld, Germany

来源：

PEDIATRIC INFECTIOUS DISEASE JOURNAL | 2009年 / 28卷 / 05期

关键词：

immunity; maternally acquired; antibodies; Bordetella pertussis; ELISA; infant; premature; INFANTS; VACCINATION; DIPHTHERIA; VACCINES;

D O I：

10.1097/INF.0b013e318193ead7

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We measured IgG-anti-pertussis toxin and -IgG-anti-filamentous hemagglutinin antibody values in 43 full term and 34 preterm infants and 79 mothers. Antibody values were generally low and mean values were higher in full term than preterm infants. Transfer ratios increased with gestational age of the newborns. Based on these findings, maternal and neonatal immunization strategies should be considered to protect young infants from pertussis.

引用

页码：443 / 445

页数：3

共 16 条

[1] Immunogenicity of a three-component acellular pertussis vaccine administered at birth [J].

Belloni, C ;

De Silvestri, A ;

Tinelli, C ;

Avanzini, MA ;

Marconi, M ;

Strano, F ;

Rondini, G ;

Chirico, G .

PEDIATRICS, 2003, 111 (05) :1042-1045

[2] The seroepidemiology of Bordetella pertussis infections: A study of persons ages 1-65 years [J].

Cattaneo, LA ;

Reed, GW ;

Haase, DH ;

Wills, MJ ;

Edwards, KM .

JOURNAL OF INFECTIOUS DISEASES, 1996, 173 (05) :1256-1259

[3] Pertussis hospitalizations among infants in the United States, 1993 to 2004 [J].

Cortese, Margaret M. ;

Baughman, Andrew L. ;

Zhang, Rongping ;

Srivastava, Pamela U. ;

Wallace, Gregory S. .

PEDIATRICS, 2008, 121 (03) :484-492

[4]

ENGLUND JA, 1995, PEDIATRICS, V96, P580

[5]

Gonik Bernard, 2005, Infect Dis Obstet Gynecol, V13, P59, DOI 10.1080/10647440500068289

[6] Prevalence of pertussis antibodies in maternal delivery, cord, and infant serum [J].

Healy, CM ;

Munoz, FM ;

Rench, MA ;

Halasa, NB ;

Edwards, KM ;

Baker, CJ .

JOURNAL OF INFECTIOUS DISEASES, 2004, 190 (02) :335-340

[7] COMPARATIVE-STUDY OF LEDERLE TAKEDA ACELLULAR AND LEDERLE WHOLE-CELL PERTUSSIS-COMPONENT DIPHTHERIA-TETANUS-PERTUSSIS VACCINES IN INFANTS IN GERMANY [J].

HEININGER, U ;

CHERRY, JD ;

CHRISTENSON, PD ;

ECKHARDT, T ;

GOERING, U ;

JAKOB, P ;

KASPER, W ;

SCHWEINGEL, D ;

LAUSSUCQ, S ;

HACKELL, JG ;

MEZZATESTA, JR ;

SCOTT, JV ;

STEHR, K .

VACCINE, 1994, 12 (01) :81-86

[8] Pertussis: an old disease that is still with us [J].

Heininger, U .

CURRENT OPINION IN INFECTIOUS DISEASES, 2001, 14 (03) :329-335

[9]

KENDRICK P, 1945, AM J DIS CHILD, V70, P25

[10] Neonatal vaccination with an acellular pertussis vaccine accelerates the acquisition of pertussis antibodies in infants [J].

Knuf, Markus ;

Schmit, Heinz-Joesf ;

Wolter, Joanne ;

Schuerman, Lode ;

Jacquet, Jeanne-Marie ;

Kieninger, Dorothee ;

Siegrist, Claire-Anne ;

Zepp, Fred .

JOURNAL OF PEDIATRICS, 2008, 152 (05) :655-660

← 1 2 →