Molecular Structure, Pathophysiology, and Diagnosis of COVID-19

被引:4
作者
Belmehdi, Omar [1 ]
Hakkour, Maryam [2 ]
El Omani, Nasreddine [3 ]
Balahbib, Abdelaali [2 ]
Guaouguaou, Fatima-Ezzahrae [4 ]
Benali, Taoufiq [5 ]
El Baaboua, Aicha [1 ]
Lahmoud, Meriem [6 ]
Elmenyiy, Naoual [7 ]
Bouyahya, Abdelhakim [8 ,9 ]
机构
[1] Abdelmalek Essaadi Univ, Fac Sci, Biotechnol & Appl Microbiol Team, Biol & Hlth Lab,Dept Biol, Tetouan, Morocco
[2] Mohammed V Univ Rabat, Fac Sci, Lab Biodivers Ecol & Genome, Rabat, Morocco
[3] Mohammed V Univ Rabat, Fac Med & Pharm, Lab Lab Histol Embryol & Cytogenet, Rabat, Morocco
[4] Mohammed V Univ Rabat, Mat Sci Ctr MSC, Ecole Normale Super, LPCMIO, Rabat, Morocco
[5] Sidi Mohamed Ben Abdellah Univ Fez, Lab Nat Resources & Environm, Polydisciplinary Fac Taza, BP 1223, Taza Gare, Taza, Morocco
[6] Cadi Ayyad Univ, Fac Med & Pharm, Marrakech, Morocco
[7] Univ Sidi Mohamed Ben Abdellah, Fac Sci, Lab Physiol Pharmacol & Environm Hlth, Fes, Morocco
[8] Mohammed V Univ Rabat, Lab Human Pathol Biol, Fac Sci, Dept Biol, Rabat, Morocco
[9] Mohammed V Univ Rabat, Genom Ctr Human Pathol, Fac Med & Pharm, Rabat, Morocco
关键词
COVID-19; SARS-CoV-2; pathophysiology; clinical diagnosis; RESPIRATORY SYNDROME SARS; SPIKE PROTEIN; FUNCTIONAL RECEPTOR; CORONAVIRUS; TRANSMISSION; INFECTION; PATHOGENESIS; GENOME;
D O I
10.33263/BRIAC113.1021510237
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
Recently, a new coronavirus, named Severe Acute Respiratory Syndrome-Coronavirus 2 (SARS-CoV-2) has emerged in Wuhan, Hubei province, China. SARS-CoV-2 caused a global epidemic (COVID-19), which continues to kill thousands of people around the world today. With an exclusively interhuman transmission mode, in the absence of a vaccine, the spreading of this new coronavirus is accelerating remarkably. With the studies of the molecular biology of the virus, molecular and serological diagnostic tests are implemented. However, the pathophysiology is not well understood and variable, which gives different symptoms, with a significant mortality rate. Indeed, several organs such as the lungs, brain, kidneys, immune system, and heart are affected directly and/or indirectly.
引用
收藏
页码:10215 / 10237
页数:23
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