STUDY OF BACTERIA RESISTANCE MECHANISMS IN RESPONSE TO A STRESS INDUCED BY PHARMACEUTICALS COMPOUNDS

被引：1
作者：
Marthe, Logan [1 ]
Stoica, Catalina [2 ]
Chiriac, Laura Florentina [2 ]
Galaon, Toma [2 ]
Nita-Lazar, Mihai [2 ]
机构：
[1] Univ Perpignan, Inst Univ Technol, Dept Genie Biol, Via Domitia, Perpignan, France
[2] Natl Res & Dev Inst Ind Ecol ECOIND Bucharest, 71-73 Drumul Podu Dambovitei, Bucharest 060652, Romania
来源：
20TH INTERNATIONAL SYMPOSIUM - THE ENVIRONMENT AND THE INDUSTRY (SIMI 2017) | 2017年
关键词：
biological adaptive markers; pharmaceutical compounds; gram-negative bacteria; defense mechanisms;
D O I：
10.21698/simi.2017.0038
中图分类号：
X [环境科学、安全科学];
学科分类号：
08 ; 0830 ;
摘要：
Three pharmaceutical compounds (Trimethoprim, Carbamazepine and Benzethonium chloride) were investigated to unveil possible toxic effects on two bacterial strains (Citrobacter freundii and Comamonas testosteroni). The pharmaceutical compounds stress triggered a bacterial defence mechanism which was evaluated at transcriptional and translational levels. In this study, potential bacterial biomarkers induced by the pharmaceutical stress were unraveled.
引用
收藏
页码：296 / 302
页数：7
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