Evaluation of the Effect of Azo Group on the Biological Activity of 1-(4-Methylphenylazo)-2-naphthol

被引:17
作者
Mkpenie, V. [1 ]
Ebong, G. [1 ]
Obot, I. B. [1 ]
Abasiekong, B. [2 ]
机构
[1] Univ Uyo, Dept Chem, Uyo, Nigeria
[2] Akwa Ibom State Polytech, Dept Sci & Technol, Ikot Ekpene, Nigeria
关键词
Azo compound; 2-Naphthol; Antibacterial activity; p-Toluidine;
D O I
10.1155/2008/438946
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Azo-2-naphthol and 2-naphthol were tested against five microorganisms: Staphylococcus aureus, Escherichia coli, Bacillus subtilis, Pseudomonas aeruginosa and Streptococcus faecalis, 2-Naphthol was slightly active while azo-2-naphthol was highly active against all the bacteria species tested. The presence of azo group contributed more than 60% of the antibacterial activities exhibited by azo-2-naphthol on all the bacteria tested.
引用
收藏
页码:431 / 434
页数:4
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