STAT1 activation in association with JAK2 exon 12 mutations

被引:8
作者
Godfrey, Anna L. [1 ,2 ,3 ,4 ]
Chen, Edwin [1 ,2 ,4 ]
Massie, Charles E. [1 ,2 ,4 ]
Silber, Yvonne [1 ,2 ,4 ]
Pagano, Francesca [1 ,2 ,4 ]
Bellosillo, Beatriz [5 ]
Guglielmelli, Paola [6 ,7 ]
Harrison, Claire N. [8 ]
Reilly, John T. [9 ]
Stegelmann, Frank [10 ]
Bijou, Fontanet [11 ]
Lippert, Eric [12 ,13 ]
Boiron, Jean-Michel [14 ]
Doehner, Konstanze [10 ]
Vannucchi, Alessandro M. [6 ,7 ]
Besses, Carlos [5 ]
Green, Anthony R. [1 ,2 ,3 ,4 ]
机构
[1] Univ Cambridge, Cambridge Inst Med Res, Cambridge, England
[2] Univ Cambridge, Wellcome Trust, MRC Stem Cell Inst, Cambridge, England
[3] Addenbrookes Hosp, Dept Haematol, Cambridge, England
[4] Univ Cambridge, Dept Haematol, Cambridge, England
[5] Hosp del Mar, IMIM, Dept Hematol, Barcelona, Spain
[6] Univ Florence, Dept Expt & Clin Med, Florence, Italy
[7] Azienda Osped Univ Careggi, Florence, Italy
[8] Guys & St Thomas NHS Fdn Trust, Dept Haematol, London, England
[9] Royal Hallamshire Hosp, Dept Haematol, Sheffield S10 2JF, S Yorkshire, England
[10] Univ Hosp Ulm, Dept Internal Med 3, Ulm, Germany
[11] Inst Bergonie, Dept Hematol, Bordeaux, France
[12] Univ Bordeaux Segalen, CHU Bordeaux, Hematol Lab, Bordeaux, France
[13] Univ Bordeaux Segalen, INSERM, Lab Hematopoiese Leucem & Cibles Therapeut, U1035, Bordeaux, France
[14] Univ Bordeaux, Etab Francais Sang, Bordeaux, France
基金
英国惠康基金;
关键词
JAK2; exon; 12; mutations; STAT1; activation; MYELOPROLIFERATIVE NEOPLASMS; POLYCYTHEMIA-VERA; DISEASE;
D O I
10.3324/haematol.2015.128546
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:E15 / E19
页数:5
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