Does Sample Size Matter When Interpreting the Fragility Index?

被引：106

作者：

Ahmed, Wael ^{[1
]}

Fowler, Robert A. ^{[1
,2
,3
]}

McCredie, Victoria A. ^{[1
,3
]}

机构：

[1] Sunnybrook Hlth Sci Ctr, Dept Crit Care Med, Toronto, ON, Canada

[2] Univ Toronto, Dept Med, Toronto, ON, Canada

[3] Univ Toronto, Inst Hlth Policy Management & Evaluat, Toronto, ON, Canada

来源：

CRITICAL CARE MEDICINE | 2016年 / 44卷 / 11期

关键词：

STATISTICAL SIGNIFICANCE; 2; PROPORTIONS; TRIALS;

D O I：

10.1097/CCM.0000000000001976

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

引用

页码：E1142 / E1143

页数：3

共 5 条

[1] The fragility of statistically significant findings from randomized trials in spine surgery: a systematic survey [J].

Evaniew, Nathan ;

Files, Carly ;

Smith, Christopher ;

Bhandari, Mohit ;

Ghert, Michelle ;

Walsh, Michael ;

Devereaux, Philip J. ;

Guyatt, Gordon .

SPINE JOURNAL, 2015, 15 (10) :2188-2197

[2] THE UNIT FRAGILITY INDEX - AN ADDITIONAL APPRAISAL OF STATISTICAL SIGNIFICANCE FOR A CONTRAST OF 2 PROPORTIONS [J].

FEINSTEIN, AR .

JOURNAL OF CLINICAL EPIDEMIOLOGY, 1990, 43 (02) :201-209

[3] The Fragility Index in Multicenter Randomized Controlled Critical Care Trials [J].

Ridgeon, Elliott E. ;

Young, Paul J. ;

Bellomo, Rinaldo ;

Mucchetti, Marta ;

Lembo, Rosalba ;

Landoni, Giovanni .

CRITICAL CARE MEDICINE, 2016, 44 (07) :1278-1284

[4] The statistical significance of randomized controlled trial results is frequently fragile: a case for a Fragility Index [J].

Walsh, Michael ;

Srinathan, Sadeesh K. ;

McAuley, Daniel F. ;

Mrkobrada, Marko ;

Levine, Oren ;

Ribic, Christine ;

Molnar, Amber O. ;

Dattani, Neil D. ;

Burke, Andrew ;

Guyatt, Gordon ;

Thabane, Lehana ;

Walter, Stephen D. ;

Pogue, Janice ;

Devereaux, P. J. .

JOURNAL OF CLINICAL EPIDEMIOLOGY, 2014, 67 (06) :622-628

[5] STATISTICAL SIGNIFICANCE AND FRAGILITY CRITERIA FOR ASSESSING A DIFFERENCE OF 2 PROPORTIONS [J].

WALTER, SD .

JOURNAL OF CLINICAL EPIDEMIOLOGY, 1991, 44 (12) :1373-1378

← 1 →