Immunological Aspects of Dental Implant Rejection

被引：55

作者：

Baseri, Milad ^{[1
]}

Radmand, Faraz ^{[2
]}

Hamedi, Reyhaneh ^{[3
]}

Yousefi, Mehdi ^{[4
,5
]}

Kafil, Hossein Samadi ^{[6
]}

机构：

[1] Tabriz Univ Med Sci, Dent & Periodontal Res Ctr, Tabriz, Iran

[2] Tabriz Univ Med Sci, Fac Dent, Biotechnol Res Ctr, Tabriz, Iran

[3] Tabriz Univ Med Sci, Sch Dent, Tabriz, Iran

[4] Tabriz Univ Med Sci, Res Ctr Pharmaceut Nanotechnol, Tabriz, Iran

[5] Tabriz Univ Med Sci, Stem Cell Res Ctr, Tabriz, Iran

[6] Tabriz Univ Med Sci, Drug Appl Res Ctr, Fac Med, Tabriz, Iran

来源：

BIOMED RESEARCH INTERNATIONAL | 2020年 / 2020卷

关键词：

PERIIMPLANT CREVICULAR FLUID; PERI-IMPLANTITIS; LANGERHANS CELLS; DENDRITIC CELLS; INFLAMMATORY CYTOKINES; CLINICAL-PARAMETERS; TITANIUM PARTICLES; TNF-ALPHA; MARKERS; HEALTHY;

D O I：

10.1155/2020/7279509

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Nowadays, dental implants are a prominent therapeutic approach among dentists for replacing missing teeth. Failure in dental implants is a severe challenge recently. The factors which lead to dental implant failure are known. These factors can be categorized into different groups. In this article, we discussed the immunological aspects of implant failure as one of these groups. Cytokines and immune cells have extensive and various functions in peri-implantitis. The equilibrium between pro and anti-inflammatory cytokines and cells, which involve in this orchestra, has a crucial role in implant prognosis. In conclusion, immune cells, especially macrophages and dendritic cells, almost increased in the patients with implant failure. Also, proinflammatory cytokines were proposed as diagnostic factors according to their higher levels in dental implant rejection.

引用

页数：12

共 102 条

[1] Hydrophilic titanium surfaces reduce neutrophil inflammatory response and NETosis [J].