Genetics: modes of reproduction and genetic analysis

被引：14
作者：
Streit, Adrian [1 ]
机构：
[1] Max Planck Inst Dev Biol, Dept Evolutionary Biol, Tubingen, Germany
来源：
PARASITOLOGY | 2017年 / 144卷 / 03期
关键词：
Strongyloides spp; genetics; parthenogenesis; sexual reproduction; sex determination; FREE-LIVING STAGES; NEMATODE STRONGYLOIDES-RATTI; PARASITIC NEMATODE; CAENORHABDITIS-ELEGANS; SEX DETERMINATION; PARASTRONGYLOIDES-TRICHOSURI; CHEMICAL MUTAGENESIS; CHROMATIN DIMINUTION; HETEROGONIC PROGENY; NUCLEAR RECEPTOR;
D O I：
10.1017/S0031182016000342
中图分类号：
R38 [医学寄生虫学]; Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ; 100103 ;
摘要：
Classical and reverse genetics remain invaluable tools for the scientific investigation of model organisms. Genetic analysis of endoparasites is generally difficult because the sexual adults required for crossing and other manipulations are usually hidden within their host. Strongyloides spp. and Parastrongyloides spp. are notable exceptions to this and their free-living adults offer unique opportunities to manipulate these parasites experimentally. Here I review the modes of inheritance in the two generations of Strongyloides/Parastrongyloides and I discuss the opportunities and the limitations of the currently available methodology for the genetic analysis of these two genera.
引用
收藏
页码：316 / 326
页数：11
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