Palladium-Catalyzed Three-Component Cascade Cyclization Reaction of Bisallenes with Propargylic Carbonates and Organoboronic Acids: Efficient Construction of cis-Fused Bicyclo[4.3.0]nonenes

被引：41

作者：

Shu, Wei ^{[1
]}

Jia, Guochen ^{[2
]}

Ma, Shengming ^{[1
]}

机构：

[1] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organometall Chem, Shanghai 200032, Peoples R China

[2] Hong Kong Univ Sci & Technol, Dept Chem, Kowloon, Hong Kong, Peoples R China

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2009年 / 48卷 / 15期

关键词：

allenes; cyclization; multicomponent reactions; palladium; tandem reactions; MULTICOMPONENT REACTIONS; ALLENES;

D O I：

10.1002/anie.200805422

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A bicycle built for two: The title reaction affords cis-fused bicyclo[4.3.0]nonenes from readily available 1,5-bisallenes with structurally diverse propargylic carbonates and arylboronic acids (see scheme; X=NTs, C(E1)2 with E1=CO2Bn, SO 2Ph, dba=trans,trans-dibenzylidenacetone). The reaction may involve a sequential oxidative addition, two different types of three carbopalladations, and a Suzuki-type coupling. © 2009 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：2788 / 2791

页数：4

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