Preparation of bromoiodopropenoic acids by stereospecific nucleophilic substitution at vinylic carbon

被引：0

作者：

Lough, Alan

McKague, A. Bruce ^{[1
]}

机构：

[1] CanSyn Chem Corp, 200 Coll St, Toronto, ON M5S 3E5, Canada

[2] Univ Toronto, Dept Chem, Toronto, ON M5S 1A1, Canada

来源：

SYNTHETIC COMMUNICATIONS | 2006年 / 36卷 / 22期

关键词：

bromoiodopropenoic acids; stereospecific substitution; vinylic carbon;

D O I：

10.1080/00397910600941430

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The bromoiodopropenoic acids (E)-2-bromo-3-iodopropenoic acid 5 and (Z)-2-bromo-3-iodopropenoic acid 6 were prepared by stereospecific nucleophilic substitution of the corresponding vinylic bromides. The structure of the (Z)-isomer was confirmed by X-ray crystallography.

引用

页码：3387 / 3391

页数：5

共 3 条

[1] Nucleophilic Substitution Reactions at Vinylic Carbons
Shen, Shusu
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2014, 34 (12) : 2448 - 2455
[2] Insights into the nucleophilic substitution of pyridine at an unsaturated carbon center
Du, Pan
Zhao, Jiyang
Liu, Shanshan
Yue, Zhen
RSC ADVANCES, 2021, 11 (39) : 24238 - 24246
[3] Nucleophilic substitution at the alkenyl and cyclopropyl carbon atoms of magnesium carbenoids: a DFT study
Kimura, Tsutomu
Satoh, Tsuyoshi
TETRAHEDRON LETTERS, 2013, 54 (37) : 5072 - 5074

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