Polyunsaturated fatty acids and neurological diseases

被引:20
作者
Salvati, S. [1 ]
Attorri, L. [1 ]
Di Benedetto, R. [1 ]
Di Biase, A. [1 ]
Leonardi, F. [1 ]
机构
[1] Ist Super Sanita, Dept Food Nutr & Hlth, I-00161 Rome, Italy
关键词
docosahexaenoic acid; eicosapentaenoic acid; arachidonic acid; neurodegenerative diseases; Alzheimer's disease; multiple sclerosis; depression; Parkinson's disease;
D O I
10.2174/138955706778742740
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
This review summarizes the knowledge of the role of dietary PUFAs, especially omega-3, on normal brain function. Furthermore, it reports the evidence pointing to potential mechanisms of omega-3 fatty acids in development of neurological disorders and efficacy of their supplementation in terms of symptom management.
引用
收藏
页码:1201 / 1211
页数:11
相关论文
共 120 条
[1]   Environmental, life-style, and physical precursors of clinical Parkinson's disease: recent findings from the Honolulu-Asia Aging Study [J].
Abbott, RD ;
Ross, GW ;
White, LR ;
Sanderson, WT ;
Burchfiel, CM ;
Kashon, M ;
Sharp, DS ;
Masaki, KH ;
Curb, JD ;
Petrovitch, H .
JOURNAL OF NEUROLOGY, 2003, 250 (Suppl 3) :30-39
[2]   MULTIPLE-SCLEROSIS AND NUTRITION [J].
ALTER, M ;
YAMOOR, M ;
HARSHE, M .
ARCHIVES OF NEUROLOGY, 1974, 31 (04) :267-272
[3]   EPIDEMIOLOGIC STUDY OF MULTIPLE SCLEROSIS IN ISRAEL .I. AN OVERALL REVIEW OF METHODS AND FINDINGS [J].
ANTONOVSKY, A ;
LEIBOWITZ, U ;
SMITH, HA ;
MEDALIE, JM ;
BALOGH, M ;
KATS, R ;
HALPERN, L ;
ALTER, M .
ARCHIVES OF NEUROLOGY, 1965, 13 (02) :183-+
[4]   Non-familial Alzheimer's disease is mainly due to genetic factors [J].
Ashford, J. Wesson ;
Mortimer, James A. .
JOURNAL OF ALZHEIMERS DISEASE, 2002, 4 (03) :169-177
[5]   Fish, meat, and risk of dementia:: cohort study [J].
Barberger-Gateau, P ;
Letenneur, L ;
Deschamps, V ;
Pérès, K ;
Dartigues, JF ;
Renaud, S .
BRITISH MEDICAL JOURNAL, 2002, 325 (7370) :932-+
[6]   MEMBRANE FATTY-ACIDS ASSOCIATED WITH ELECTRICAL RESPONSE IN VISUAL EXCITATION [J].
BENOLKEN, RM ;
ANDERSON, RE ;
WHEELER, TG .
SCIENCE, 1973, 182 (4118) :1253-1254
[7]   RISK-FACTORS IN MULTIPLE-SCLEROSIS - A POPULATION-BASED CASE-CONTROL STUDY IN HAUTES-PYRENEES, FRANCE [J].
BERR, C ;
PUEL, J ;
CLANET, M ;
RUIDAVETS, JB ;
MAS, JL ;
ALPEROVITCH, A .
ACTA NEUROLOGICA SCANDINAVICA, 1989, 80 (01) :46-50
[8]   Erythrocyte membrane fatty acid composition of smokers and non-smokers: effects of vitamin E supplementation [J].
Brown, KM ;
Morrice, PC ;
Duthie, GG .
EUROPEAN JOURNAL OF CLINICAL NUTRITION, 1998, 52 (02) :145-150
[9]  
Burr GO, 1929, J BIOL CHEM, V82, P345
[10]   Fat chance of immunomodulation [J].
Calder, PC .
IMMUNOLOGY TODAY, 1998, 19 (06) :244-247