Silver-catalyzed fluoroalkylation of thiols using fluoroalkanesulfinates

被引：41

作者：

Ma, Jing-jing ^{[1
]}

Liu, Qi-ran ^{[1
]}

Lu, Guo-ping ^{[1
]}

Yi, Wen-bin ^{[1
]}

机构：

[1] Nanjing Univ Sci & Technol, Chem Engn Coll, 200 Xiaolingwei, Nanjing 210094, Jiangsu, Peoples R China

来源：

JOURNAL OF FLUORINE CHEMISTRY | 2017年 / 193卷

基金：

中国国家自然科学基金;

关键词：

Silver-catalyzed; Fluoroalkylation; Fluoroalkanesulfinates; Thiols; ALIPHATIC CARBOXYLIC-ACIDS; TRIFLUOROMETHYL SULFIDES; NUCLEOPHILIC TRIFLUOROMETHYLATION; SODIUM TRIFLUOROMETHANESULFINATE; ARYL; HALIDES; PERFLUOROALKYLATION; TRIMETHYLSILANE; DIFLUOROMETHYL; DERIVATIVES;

D O I：

10.1016/j.jfluchem.2016.11.010

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

A practical sliver-catalyzed fluoroalkylation of aryl-, heteroaryl- and allcylthiols has been developed. The reaction has a good functional-group tolerance and excellent selectivity. A variety of stable and solid fluoroalkanesulfinates including di- and perfluoroalkanesulfinates can be employed. This methodology provides a straightforward and streamlined access to perfluoroallcylthiolated organic molecules. [GRAPHICS] (C) 2016 Elsevier B.V. All rights reserved.

引用

页码：113 / 117

页数：5

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