A radical-based strategy for the synthesis of higher homologues of sinefungin

被引：0

作者：

Maria, EJ

da Silva, AD

Fourrey, JL ^{[3
]}

机构：

[1] Univ Estadual N Fluminen, CCT, Lab Ciencias Quim, BR-28015620 Campos dos Goytacazes, RJ, Brazil

[2] Univ Fed Juiz De Fora, ICE, Dept Quim, BR-36036330 Juiz De Fora, MG, Brazil

[3] CNRS, Inst Chim Subst Nat, F-91198 Gif Sur Yvette, France

来源：

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2000年 / 2000卷 / 04期

关键词：

complex nucleoside; antibiotics; radical; Zn-Cu couple;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Homosinefungin 5, which can be considered as an analogue of S-adenosylmethionine (SAM) and of S-adenosylhomocysteine (SAH), has been synthesized by means of a sequence in which the key step was the addition of a radical, produced by the simple treatment of an iodide precursor with a zinc-copper couple, to suitably activated olefins.

引用

页码：627 / 631

页数：5