Computed Tomography-Based Tumor Volume in Non-Hodgkin Lymphoma: Clinical Correlation and Comparison With Magnetic Resonance Imaging

被引：3

作者：

Rossi, Maija ^{[1
]}

Pertovaara, Hannu ^{[2
]}

Dastidar, Prasun ^{[1
,4
]}

Jarvenpaa, Ritva ^{[1
]}

Luukkaala, Tiina ^{[3
,5
]}

Rautakunnas, Sylvia ^{[1
,4
]}

Heinonen, Tomi ^{[6
]}

Eskola, Hannu ^{[1
,6
]}

Soimakallio, Seppo ^{[1
,4
]}

Kellokumpu-Lehtinen, Pirkko-Liisa ^{[2
,4
]}

机构：

[1] Tampere Univ Hosp, Dept Diagnost Radiol, Reg Med Imaging Ctr, Tampere 33521, Finland

[2] Tampere Univ Hosp, Dept Oncol, Tampere 33521, Finland

[3] Pirkanmaa Univ Hosp Dist, Ctr Sci, Tampere, Finland

[4] Pirkanmaa Univ Hosp Dist, Tampere Med Sch, Tampere, Finland

[5] Univ Tampere, Tampere Sch Publ Hlth, FIN-33101 Tampere, Finland

[6] Tampere Univ Technol, Dept Biomed Engn, FIN-33101 Tampere, Finland

来源：

JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY | 2009年 / 33卷 / 04期

关键词：

computed tomography; non-Hodgkin lymphoma; response monitoring; volumetric analysis; LARGE-CELL LYMPHOMA; POSITRON-EMISSION-TOMOGRAPHY; THERAPEUTIC RESPONSE; SOLID TUMORS; CT; SEGMENTATION; CRITERIA; DISEASE; VARIABILITY; LESIONS;

D O I：

10.1097/RCT.0b013e3181885971

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Objectives: To evaluate the prognostic significance of tumor volume in computed tomographic (CT) images of non-Hodgkin lymphoma patients. To compare CT volumes with those measured by magnetic resonance imaging (MRI). Methods: Twenty-five patients with B cell-type non-Hodgkin lymphoma (16 men, 9 women, age range, 48-77 years) were imaged with CT at 5 time points. The volumes and volume reductions were associated with clinical characteristics and treatment outcome. The CT-derived tumor volumes were correlated with MRI volumes derived earlier for the same patients. Results: Good agreement was found between 1-dimensional (1D), 2D, and 3D analyses. The CT-derived median turner volumes were 306 cm 3, 174 cm(3), 75 cm(3), 28 cm(3), and 15 cm(3) at the 5 time points. These volumes were found to associate, for example, with mortality and tumor malignancy. The CT-based tumor volumes showed good correlation with MRI. Conclusions: Tumor volume quantification is a powerful tool that associates with clinical characteristics and treatment outcome.

引用

页码：641 / 649

页数：9

共 42 条

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