α-Haloarylsulfonamides: multiple cyclization pathways to skeletally diverse benzofused sultams

被引：79
作者：
Rayabarapu, Dinesh Kumar [1 ,2 ]
Zhou, Aihua [1 ,2 ]
Jeon, Kyu Ok [1 ,2 ]
Samarakoon, Thiwanka [1 ,2 ]
Rolfe, Alan [1 ,2 ]
Siddiqui, Hina [1 ,2 ]
Hanson, Paul R. [1 ,2 ]
机构：
[1] Univ Kansas, Dept Chem, Lawrence, KS 66045 USA
[2] Univ Kansas, Ctr Chem Methodol & Lib Dev, Lawrence, KS 66047 USA
来源：
TETRAHEDRON | 2009年 / 65卷 / 16期
关键词：
ORIENTED SYNTHESIS; DERIVATIVES; METATHESIS; MICHAEL; AGENTS;
D O I：
10.1016/j.tet.2008.11.053
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The development of new methods to skeletally diverse sultams based oil a central alpha-halo benzene sulfonamide building block is reported. Several salient features of this building block are Utilized ill multiple reaction pathways, including the Fleck reaction, C- and O-arylation, Sonogashira-Pauson-Khand, Sonogashira-intramolecular hydroamination, and domino aza-Michael-Heck for the generation of five-, six-, and seven-membered benzofused bicyclic and tricyclic sultams. (C) 2008 Elsevier Ltd. All rights reserved.
引用
收藏
页码：3180 / 3188
页数：9
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