Bacillus thuringiensis crystal δ-endotoxin:: Role of proteases in the conversion of protoxin to toxin

被引:50
|
作者
Rukmini, V [1 ]
Reddy, CY [1 ]
Venkateswerlu, G [1 ]
机构
[1] Osmania Univ, Dept Biochem, Hyderabad 500007, Andhra Pradesh, India
关键词
Bacillus thuringiensis; delta-endotoxin; protoxins; mature toxins; proteases;
D O I
10.1016/S0300-9084(00)00355-2
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The conversion of delta-endoprotoxins of Bacillus thuringiensis to active toxins is mediated by trypsin, insect gut (exogenous) and bacterial (endogenous) proteases. The biochemical aspects of exogenous and endogenous proteases involved in the conversion of protoxin to toxin are reviewed. Perhaps, these proteases also play a role in influencing the host range of toxin and in the development of resistance to toxin. (C) 2000 Societe francaise de biochimie et biologie moleculaire / Editions scientifiques ct medicales Elsevier SAS.
引用
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页码:109 / 116
页数:8
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