Photoaging: Mechanisms and repair

被引：396
作者：
Rabe, Jessica H. [1 ]
Mamelak, Adam J. [1 ]
McElgunn, Patrick J. S. [1 ]
Morison, Warwick L. [1 ]
Sauder, Daniel N. [1 ]
机构：
[1] Johns Hopkins Univ, Dept Dermatol, Baltimore, MD 21218 USA
来源：
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY | 2006年 / 55卷 / 01期
关键词：
D O I：
10.1016/j.jaad.2005.05.010
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
Aging is a complex, multifactorial process resulting in several functional and esthetic changes in the skin. These changes result from intrinsic as well as extrinsic processes, such as ultraviolet radiation. Recent advances in skin biology have increased our understanding of skin homeostasis and the aging process, as well as the mechanisms by which ultraviolet radiation contributes to photoaging and cutaneous disease. These advances in skin biology have led to the development of a diversity of treatments aimed at preventing aging and rejuvenating the skin. The focus of this review is the mechanism of photoaging and the pathophysiology underlying the treatments specifically designed for its prevention and treatment.
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页码：1 / 19
页数：19
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