Near infrared transflectance spectroscopy Determination of dexketoprofen in a hydrogel

被引：11

作者：

Blanco, M ^{[1
]}

Romero, MA ^{[1
]}

机构：

[1] Univ Autonoma Barcelona, Fac Ciencies, Dept Quim, Unitat Quim Analit, E-08193 Bellaterra, Spain

来源：

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS | 2002年 / 30卷 / 03期

关键词：

near infrared spectroscopy; transflectance; dexketoprofen; hydrogel;

D O I：

10.1016/S0731-7085(02)00093-6

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A new method for the determination of the active principle dexketoprofen (DKP) in a hydrogel using near infrared spectrometry was developed. A transflectance module allows the gel spectrum to be recorded with no sample pretreatment. Also, the PLS calibration method used allows low contents of the active principle in such a highly absorbing matrix as water/ethanol to be determined. The proposed method was validated and found to be an effective choice for the intended purpose. (C) 2002 Published by Elsevier Science B.V.

引用

页码：467 / 472

页数：6

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