Bilateral Anterior Granulomatous Keratouveitis with Sunset Glow Fundus in a Patient with Autoimmune Polyglandular Syndrome

被引：9

作者：

Futagami, Yuri

Sugita, Sunao ^{[1
]}

Fujimaki, Takuro ^{[2
]}

Yokoyama, Toshiyuki ^{[2
]}

Morio, Tomohiro ^{[3
]}

Mochizuki, Manabu

机构：

[1] Tokyo Med & Dent Univ, Grad Sch Med, Dept Ophthalmol & Visual Sci, Bunkyo Ku, Tokyo 1138519, Japan

[2] Juntendo Univ, Sch Med, Dept Ophthalmol, Tokyo 113, Japan

[3] Tokyo Med & Dent Univ, Grad Sch Med, Dept Pediat & Dev Biol, Tokyo 1138519, Japan

来源：

OCULAR IMMUNOLOGY AND INFLAMMATION | 2009年 / 17卷 / 02期

关键词：

keratouveitis; melanocyte; pediatric; autoimmune disease; DISEASE;

D O I：

10.1080/09273940802596518

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

Aim: To report the case of a patient with bilateral anterior granulomatous keratouveitis and sunset glow fundus. Method: Review of case record. Results: A 15-year-old patient had bilateral anterior granulomatous keratouveitis and sunset glow fundus similar to findings in Vogt-Koyanagi-Harada disease (VKH). However, the patient also suffered additional autoimmune disease against endocrine glands. In addition to anti-thyroid antibody and anti-glutamic acid decarboxylase antibody, anti-melanocyte autoantibody was detected in serum from this patient. The authors finally diagnosed autoimmune polyglandular syndrome. Conclusion: If resistance against treatment exists for VKH, particularly in pediatric cases, this disease should be considered and other endocrine disorders examined.

引用

页码：88 / 90

页数：3

共 5 条

[1]

Eisenbarth GS, 2004, ADV EXP MED BIOL, V552, P204

[2] The Vogt-Koyanagi-Harada syndrome: Association with autoimmune polyglandular syndrome type 1 [J].