Pre-Eclampsia and Future Cardiovascular Risk Among Women A Review

被引：243
作者：
Ahmed, Raheel [1 ]
Dunford, Joseph [1 ]
Mehran, Roxana [2 ]
Robson, Stephen [3 ,4 ]
Kunadian, Vijay [4 ,5 ]
机构：
[1] Newcastle Univ, Fac Med Sci, Sch Med, Newcastle Upon Tyne NE2 4HH, Tyne & Wear, England
[2] Mt Sinai Sch Med, New York, NY USA
[3] Newcastle Univ, Uterine Cell Signaling Grp, Newcastle Upon Tyne NE2 4HH, Tyne & Wear, England
[4] Newcastle Univ, Fac Med Sci, Inst Cellular Med, Newcastle Upon Tyne NE2 4HH, Tyne & Wear, England
[5] Newcastle Upon Tyne Hosp NHS Fdn Trust, Freeman Hosp, Ctr Cardiothorac, Newcastle Upon Tyne, Tyne & Wear, England
来源：
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY | 2014年 / 63卷 / 18期
关键词：
acute coronary syndrome; angina; coronary artery disease; endothelium; hypertension; myocardial infarction; pre-eclampsia; vascular function; HYPERTENSIVE PREGNANCY DISORDERS; AMERICAN-HEART-ASSOCIATION; DISEASE RISK; RETROSPECTIVE COHORT; VASCULAR DYSFUNCTION; LATER LIFE; FOLLOW-UP; HEALTH; HISTORY; STROKE;
D O I：
10.1016/j.jacc.2014.02.529
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Cardiovascular disease continues to be the leading cause of death in the western world. Due to advancements in diagnosis, prevention, and treatment, cardiovascular mortality has fallen in recent years. Previous studies have evaluated the impact of traditional risk factors such as hypercholesterolemia and smoking. However, limited studies have been conducted to evaluate sex discrepancies among patients with cardiovascular disease. Pre-eclampsia is a multisystem placentally mediated disease, which usually arises after 32 weeks of gestation and classically presents with hypertension and proteinuria. Pre-eclampsia affects 2% to 8% of all pregnancies worldwide and is often complicated by fetal growth restriction. Women with a history of pre-eclampsia are at increased risk of future cardiovascular complications. Therefore, this topic is of significance to the cardiovascular health of over 300 million women worldwide. The goal of this review is to determine the association of pre-eclampsia and future cardiovascular risk and to explore the potential management options for these high-risk women. (C) 2014 by the American College of Cardiology Foundation
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页码：1815 / 1822
页数：8
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