Three New 24-Nortriterpenoids from the Roots of Ilex asprella

被引:8
|
作者
Jiang, Kun [1 ]
Bai, Jun-Qi [1 ,2 ]
Chang, Jun [3 ]
Tan, Jun-Jie [1 ]
Qu, Shi-Jin [1 ]
Luo, Hong-Feng [1 ]
Tan, Chang-Heng [1 ]
Zhu, Da-Yuan [1 ,2 ]
机构
[1] Chinese Acad Sci, Shanghai Inst Mat Med, Dept Nat Med Chem, Shanghai 201203, Peoples R China
[2] Guangzhou Univ Chinese Med, Affiliated Clin Hosp 2, Guangzhou 510006, Guangdong, Peoples R China
[3] Fudan Univ, Sch Pharm, Dept Nat Prod Chem, Shanghai 201203, Peoples R China
基金
中国国家自然科学基金;
关键词
Ilex asprella; Triterpenoids; 24-Nortriterpenoids; Asprellols A-C; GLYCOSIDIC CONSTITUENTS; MELICOPE-PTELEIFOLIA;
D O I
10.1002/hlca.201300147
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Asprellols A-C (1-3, resp.), three new 24-nortriterpenoids, were isolated from the CHCl3-soluble fraction of 95% EtOH extract of the roots of Ilex asprella, together with a known nortriterpenoid. The structures of the new compounds were elucidated as 2,6,20-trihydroxy-3-oxo-11,12-epoxy-24-norursa-1,4-dien-28,13-olide (1), 2,6-dihydroxy-3-oxo-11,12-epoxy-24-norursa-1,4,20(30)-trien-28,13-olide (2), and 2,6-dihydroxy-3-oxo-11,12-epoxy-24-noroleana-1,4-dien-28,13-olide (3) on the basis of spectroscopic analyses.
引用
收藏
页码:64 / 69
页数:6
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