A Versatile Setup for Time-Resolved Functional Near Infrared Spectroscopy Based on Fast-Gated Single-Photon Avalanche Diode and on Four-Wave Mixing Laser

被引：8

作者：

Di Sieno, Laura ^{[1
]}

Dalla Mora, Alberto ^{[1
]}

Torricelli, Alessandro ^{[1
,2
]}

Spinelli, Lorenzo ^{[2
]}

Re, Rebecca ^{[1
,2
]}

Pifferi, Antonio ^{[1
,2
]}

Contini, Davide ^{[1
]}

机构：

[1] Politecn Milan, Dipartimento Fis, Piazza Leonardo da Vinci 32, I-20133 Milan, Italy

[2] CNR, Ist Foton & Nanotecnol, Piazza Leonardo da Vinci 32, I-20133 Milan, Italy

来源：

APPLIED SCIENCES-BASEL | 2019年 / 9卷 / 11期

关键词：

time-domain NIRS; null source-detector separation; brain; diffuse optics; DYNAMIC-RANGE;

D O I：

10.3390/app9112366

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

In this paper, a time-domain fast gated near-infrared spectroscopy system is presented. The system is composed of a fiber-based laser providing two pulsed sources and two fast gated detectors. The system is characterized on phantoms and was tested in vivo, showing how the gating approach can improve the contrast and contrast-to-noise-ratio for detection of absorption perturbation inside a diffusive medium, regardless of source-detector separation.

引用

页数：11

共 27 条

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