Green Synthesis of 1,2,4,5-Tetrasubstituted and 2,4,5-Trisubstituted Imidazole Derivatives Involving One-pot Multicomponent Reaction

被引：26

作者：

Bansal, Ravi ^{[1
]}

Soni, Pradeep K. ^{[1
]}

Halve, Anand K. ^{[1
]}

机构：

[1] Jiwaji Univ, Sch Studies Chem, Gwalior 474011, Madhya Pradesh, India

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 2018年 / 55卷 / 06期

关键词：

SOLVENT-FREE CONDITIONS; HIGHLY SUBSTITUTED IMIDAZOLES; EFFICIENT SYNTHESIS; ALPHA-HYDROXYKETONE; CATALYST; BENZIMIDAZOLES; ANTIBACTERIAL; 2,4,5-TRIARYL; CHLORIDE; ACETATE;

D O I：

10.1002/jhet.3160

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Sodium lauryl sulfate has been found convenient, versatile, and eco-friendly catalyst for the synthesis of 1,2,4,5-tetrasubstituted and 2,4,5-trisubstituted imidazole derivatives by one-pot multicomponent reactions at 80 degrees C using water as solvent. This protocol afforded advantages, that is, the metal-free reaction, purification of products by non-chromatographic method, and excellent yields.

引用

页码：1308 / 1312

页数：5

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