Studies towards the total synthesis of batzelladine A

被引：48
|
作者：
Elliott, MC [1 ]
Long, MS [1 ]
机构：
[1] Cardiff Univ, Sch Chem, Cardiff CF10 3TB, S Glam, Wales
来源：
ORGANIC & BIOMOLECULAR CHEMISTRY | 2004年 / 2卷 / 14期
关键词：
D O I：
10.1039/b404679j
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Application of a diastereoselective three-component coupling to the bicyclic core of the batzelladine alkaloids is described. The synthesis features the elaboration of glutamic acid by use of Eschenmoser sulfide contraction. An earlier approach is also included, which shows some limitations of dithiane chemistry when applied to the particular compounds required for this target.
引用
收藏
页码：2003 / 2011
页数：9
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