Non-functional parathyroid carcinoma: a case report and review of the literature

被引:19
作者
Wang, Liang [1 ,2 ,3 ]
Han, Dali [4 ]
Chen, Wanjun [1 ]
Zhang, Shuguang [1 ]
Wang, Zhiqi [1 ]
Li, Ke [1 ]
Gao, Yongsheng [5 ]
Zou, Shujuan [1 ]
Yang, Aiju [1 ]
机构
[1] Shandong Canc Hosp & Inst, Dept Head & Neck Surg, Jinan, Peoples R China
[2] Jinan Univ, Dept Med, Jinan, Peoples R China
[3] Jinan Univ, Shandong Acad Med Sci, Life Sci Coll, Jinan, Peoples R China
[4] Shandong Canc Hosp & Inst, Dept Radiat Oncol, Jinan, Peoples R China
[5] Shandong Canc Hosp & Inst, Dept Pathol, Jinan, Peoples R China
关键词
carcinoma; non-functional; parathyroid; surgery; GLAND CARCINOMA; CANCER; FEATURES; DIAGNOSIS; TUMORS; MANAGEMENT; ADENOMA; LIGHT; NECK;
D O I
10.1080/15384047.2015.1070989
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Non-functional parathyroid carcinoma is an exceedingly rare disease with 31 reported cases since 1909. Because of the scarce number of cases of non-functional parathyroid carcinoma, there are no evidence-based recommendations for its optimal treatment. Surgery, including en bloc resection of the carcinoma, ipsilateral thyroid lobe and isthmus together with a neck dissection only in case of lymph node involvement, is the main treatment for non-functioning parathyroid carcinoma. The patient usually has a poorer prognosis because of detection at advanced stages, the relative ineffectiveness of adjuvant treatment modalities and the lack of adequate parameters for clinical follow-up. In this report, we present a case of non-functional parathyroid carcinoma at our institution, and we review the previous literature to discuss the latest advances in the diagnosis and treatment of this rare disease.
引用
收藏
页码:1569 / 1576
页数:8
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