SYNTHESIS OF 1-AMINOMETHYL-5-SUBSTITUTED-3-{4′-(2"-CHLOROBENZYLOXY)-BENZOYLHYDRAZONO)-INDOLIN-2-ONES AS ANTIFUNGAL AGENTS

被引：0

作者：

Rastogi, Nisheeth ^{[1
]}

Kant, Padam ^{[2
]}

Harrison, Darwin Anil ^{[1
]}

Sethi, Rakesh ^{[2
]}

Tripathi, Diwakar ^{[3
]}

机构：

[1] Lucknow Christian Post Grad Coll, Dept Chem, Lucknow 226018, Uttar Pradesh, India

[2] Univ Lucknow, Dept Chem, Lucknow 226007, Uttar Pradesh, India

[3] Sri Jain Narain Postgrad Coll, Dept Chem, Lucknow 226001, Uttar Pradesh, India

来源：

INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY | 2009年 / 18卷 / 03期

关键词：

DERIVATIVES; HYDRAZONES;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

5-Substituted-3-{4'-(2"-chlorobenzyloxy)-benzoylhydrazono}-indolin-2-ones 3-6 were synthesized by the condensation of 4-(2'-chlorobenzyloxy)-benzoylhydrazine 2 and 5-substituted indole-2,3-diones. Mannich reaction in the presence of formaldehyde and heterocyclic secondary amines on 3-6 furnished 1-aminomethyl-5-substituted-3-{4'-(2"-chlorobenzyloxy)-benzoylhydrazono}-indolin-2-ones 7-22.

引用

页码：263 / 266

页数：4

共 7 条

[1]

CAVIER R, 1969, CHIM INDUSTR-MILAN, V4, P21

[2]

Meenakshi K, 2006, INDIAN J HETEROCY CH, V16, P21

[3]

OSDANE TS, 1970, MED CHEM, P662

[4]

Popp FD., 1975, ADV HETERCYCL CHEM, V18, P1, DOI [10.1016/S0065-2725(08)60127-0, DOI 10.1016/S0065-2725(08)60127-0]

[5] Synthesis and antibacterial screening of hydrazones, Schiff and Mannich bases of isatin derivatives [J].

Sridhar, SK ;

Saravanan, M ;

Ramesh, A .

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2001, 36 (7-8) :615-625

[6]

Varma R. S., 1980, INDIAN J PHARM SCI, V43, P8

[7]

Varma RS, 2000, INDIAN J HETEROCY CH, V9, P223

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