Synthesis, antibacterial and antifungal activities of 3-(1,2,4-triazol-3-yl)-4-thiazolidinones

被引：0

作者：

Ozkirimli, Sumru ^{[1
]}

Kazan, Fusun ^{[1
]}

Tunali, Yagmur ^{[2
]}

机构：

[1] Istanbul Univ, Fac Pharm, Dept Pharmaceut Chem, TR-34116 Istanbul, Turkey

[2] Anadolu Univ, Fac Pharm, Dept Pharmaceut Microbiol, Eskisehir, Turkey

来源：

JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY | 2009年 / 24卷 / 02期

关键词：

1; 2; 4-Triazole; 4-thiazolidinone; antifungal; antibacterial; DERIVATIVES; BIOSYNTHESIS; TRIAZOLE;

D O I：

10.1080/14756360802188511

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A new series of 3-(1,2,4-triazol-3-yl)-4-thiazolidinone derivatives has been synthesized by the reaction of Schiff bases of 3-amino-1,2,4-triazoles with mercaptoacetic acid and 2-mercaptopropionic acid. Their antibacterial and antifungal activities were evaluated against S. aureus, S. epidermidis, C. albicans and C. glabrata.

引用

页码：447 / 452

页数：6

共 20 条

[1] Ergosterol biosynthesis pathway in Aspergillus fumigatus [J].

Alcazar-Fuoli, Laura ;

Mellado, Emilia ;

Garcia-Effron, Guillermo ;

Lopez, Jordi R. ;

Grimalt, Joan O. ;

Cuenca-Estrella, J. Manuel ;

Rodriguez-Tudela, Juan L. .

STEROIDS, 2008, 73 (03) :339-347

[2] Antifungal pharmacokinetics and pharmacodynamics: understanding the implications for antifungal drug resistance [J].

Andes, D .

DRUG RESISTANCE UPDATES, 2004, 7 (03) :185-194

[3]

[Anonymous], 2002, CLSI document M27-A2, V2nd

[4]

Barry A.L., 1985, Manual of Clinical Microbiology, V4th, P978

[5] New 6-phenylimidazo[2,1-b]thiazole derivatives:: Synthesis and antifungal activity [J].

Çapan, G ;

Ulusoy, N ;

Ergenç, N ;

Kiraz, M .

MONATSHEFTE FUR CHEMIE, 1999, 130 (11) :1399-1407

[6] Synthesis and antifungal activity of new thienyl and aryl conazoles [J].

Chevreuil, Francis ;

Landreau, Anne ;

Seraphin, Denis ;

Larcher, Gerald ;

Bouchara, Jean-Philippe ;

Richomme, Pascal .

JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2006, 21 (03) :293-303

[7]

DEEB A, 1986, Egyptian Journal of Pharmaceutical Sciences, V27, P37

[8]

Ergenç N, 1999, ARCH PHARM, V332, P343, DOI 10.1002/(SICI)1521-4184(199910)332:10<343::AID-ARDP343>3.0.CO

[9]

2-0

[10] Synthesis and antifungal activities of some aryl [3-(imidazol-1-yl/triazol-1-ylmethyl) benzofuran-2-yl] ketoximes [J].

Gundogdu-Karaburun, Nalan ;

Benkli, Kadriye ;

Tunali, Yagmur ;

Ucucu, Umit ;

Demirayak, Seref .

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2006, 41 (05) :651-656

← 1 2 →