Discovery of novel allosteric inhibitors of HCV NS3/4a enzyme via structure-based drug design Discovery of novel allosteric inhibitors of HCV NS3/4a enzyme via structure-based drug design

被引：0

作者：

Pathuri, Puja ^{[1
]}

Saalau-Bethell, Susanne M. ^{[1
]}

Woodhead, Andrew J. ^{[1
]}

Carr, Maria G. ^{[1
]}

Chessari, Gianni ^{[1
]}

Coyle, Joseph ^{[1
]}

Frederickson, Martyn ^{[1
]}

Graham, Brent ^{[1
]}

Hamlett, Chris ^{[1
]}

Hiscock, Steven D. ^{[1
]}

Holding, Finn P. ^{[1
]}

Jhoti, Harren ^{[1
]}

McMenamin, Rachel ^{[1
]}

Murray, Chris W. ^{[1
]}

Reader, Mike ^{[1
]}

Rees, David C. ^{[1
]}

Rich, Sharna J. ^{[1
]}

Richardson, Caroline J. ^{[1
]}

Thompson, Neil ^{[1
]}

Verdonk, Marcel L. ^{[1
]}

Vinkovic, Mladen ^{[1
]}

Williams, Pamela A. ^{[1
]}

Yon, Jeff ^{[1
]}

机构：

[1] Astex Pharmaceut, Cambridge CB4 0QA, England

来源：

ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES | 2012年 / 68卷

关键词：

protein crystallography drug design; fragment screening; antiviral drug;

D O I：

10.1107/S0108767312099473

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

MS7-04

引用

页码：S27 / S27

页数：1