Discovery and Development of Aurora Kinase Inhibitors as Anticancer Agents

被引：167
作者：
Pollard, John R. [1 ]
Mortimore, Michael [1 ]
机构：
[1] Vertex Pharmaceut Europe Ltd, Abingdon OX14 4RY, Oxon, England
来源：
JOURNAL OF MEDICINAL CHEMISTRY | 2009年 / 52卷 / 09期
关键词：
SMALL-MOLECULE INHIBITOR; CHROMOSOMAL PASSENGER PROTEIN; SPINDLE-ASSEMBLY CHECKPOINT; CYCLE-DEPENDENT EXPRESSION; SUPPRESSES TUMOR-GROWTH; I DOSE-ESCALATION; B-KINASE; A KINASE; CELL-DIVISION; HISTONE H3;
D O I：
10.1021/jm8012129
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
[No abstract available]
引用
收藏
页码：2629 / 2651
页数：23
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