Proteomics of Human Teeth and Saliva

被引：37

作者：

Jagr, M. ^{[1
]}

Eckhardt, A. ^{[1
]}

Pataridis, S. ^{[1
]}

Broukal, Z. ^{[2
,3
]}

Duskova, J. ^{[2
,3
]}

Miksik, I. ^{[1
]}

机构：

[1] Acad Sci Czech Republ, Inst Physiol, Dept Anal Biol Important Cpds, CR-14220 Prague 4, Czech Republic

[2] Charles Univ Prague, Fac Med 1, Inst Clin & Expt Dent Med, Prague, Czech Republic

[3] Gen Univ Hosp Prague, Prague, Czech Republic

来源：

PHYSIOLOGICAL RESEARCH | 2014年 / 63卷

关键词：

Proteomics; Tooth; Dentin; Enamel; Pulp; HUMAN DENTAL-PULP; NONCOLLAGENOUS MATRIX PROTEINS; ODONTOGENIC DIFFERENTIATION; DENTINOGENESIS IMPERFECTA; STEM-CELLS; IN-VITRO; ENAMEL; EXPRESSION; SIALOPHOSPHOPROTEIN; PHOSPHOPROTEIN;

D O I：

10.33549/physiolres.932702

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

Teeth have been a focus of interest for many centuries - due to medical problems with them. They are the hardest part of the human body and are composed of three mineralized parts enamel, dentin and cementum, together with the soft pulp. However, saliva also has a significant impact on tooth quality. Proteomic research of human teeth is now accelerating, and it includes all parts of the tooth. Some methodological problems still need to be overcome in this research field - mainly connected with calcified tissues. This review will provide an overview of the current state of research with focus on the individual parts of the tooth and pellicle layer as well as saliva. These proteomic results can help not only stomatology in terms of early diagnosis, identifying risk factors, and systematic control.

引用

页码：S141 / S154

页数：14

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