Pruritus sine materia: a prospective study of 95 patients

被引:27
作者
Afifi, Y
Aubin, F
Puzenat, E
Degouy, A
Aubrion, D
Hassam, B
Humbert, P
机构
[1] CHU St Jacques, Serv Dermatol 1, F-25030 Besancon, France
[2] CHU Rabat, Hop Ibn Sina, Serv Dermatol, Rabat, Morocco
来源
REVUE DE MEDECINE INTERNE | 2004年 / 25卷 / 07期
关键词
pruritus sine material; etiology; systemic diseases;
D O I
10.1016/j.revmed.2003.12.015
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Purpose. - To describe the nature and the frequency of systemic diseases responsible for the pruritus sine materia. Value of this sign as a marker of malignancy. Methods. - Prospective study undertaken over five years (1996-2001). Inclusion criteria: generalized aspect of the pruritus and absence of specific primitive cutaneous lesions of an itching dermatosis. Parameters taken from the data of the anamnesis and the physical examination. Standard biologic and morphologic investigations were done. Results. - Ninety-five patients included (54 men, 41 women) of 55.5 years average age 18.1. In 24 patients, traditional hospitalisation with one average duration of eight days stay +/-3.15 was necessary. In 38 cases (40%), a systemic cause was found. The main conditions were: toxocariasis (8 cases), hematologic diseases (7 cases), chronic renal failure (6 cases), hypothyroidism (5 cases) and iron deficiency (5 cases). A neoplasm was found in eight cases (8,42%): seven hematologic malignancy (3 myeloma, 2 Hodgkin's diseases, 2 myeloproliferative syndromes) and one solid cancer (pulmonary adenocarcinoma). Conclusion. - A systemic aetiology was observed in 38 cases (40%). The toxocariasis an underestimated disease comes at the first place. The pruritus sine materia can hide an hematologic malignancy. (C) 2003 Elsevier SAS. Tous droits reserves.
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页码:490 / 493
页数:4
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