Hemoadsorption cartridge and coronavirus disease 2019 infections: A case report and brief literature review

被引:8
作者
Melegari, Gabriele [1 ]
Bertellini, Elisabetta [1 ]
Melegari, Alessandra [2 ]
Trenti, Tommaso [2 ]
Malaguti, Silvio [3 ]
Barbieri, Alberto [3 ]
机构
[1] Azienda Osped Univ Modena, Dept Anaesthesia & Intens Care, Modena, Italy
[2] Azienda Unita Sanit Locale, Dept Lab Med, Modena, Italy
[3] Univ Modena & Reggio Emilia, Sch Anaesthesia & Intens Care, Modena, Italy
关键词
coronavirus disease 2019 outbreak; cytokine storm; hemoadsorption; CYTOKINE STORM;
D O I
10.1111/aor.13846
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
The cytokine storm has been frequently reported to occur in patients with severe coronavirus disease 2019 (COVID-19). Data from the literature suggest that elevated levels of inflammatory mediators, such as interleukin (IL)-6, IL-8, and tumor necrosis factor, indicate a severe course or the fatality of the disease. Several therapeutic options have been employed to treat critically ill patients, including hemoadsorption of inflammatory mediators. We here present a case of severe acute respiratory syndrome caused by COVID-19 and acute renal failure. The patient was admitted to our intensive care unit and treated with mechanical ventilation, renal replacement therapy, and hemoadsorption to reduce the cytokine release syndrome, which plays a fundamental role in the clinical presentation of COVID-19 patients. We also discuss the potential advantages of reducing cytokine plasma levels using a hemoadsorption cartridge.
引用
收藏
页码:E130 / E135
页数:6
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