Triphase Interface Synthesis of Plasmonic Gold Bellflowers as Near-Infrared Light Mediated Acoustic and Thermal Theranostics

被引：187
作者：
Huang, Peng [1 ]
Rong, Pengfei [1 ,2 ,4 ]
Lin, Jing [1 ]
Li, Wanwan [1 ]
Yan, Xuefeng [1 ]
Zhang, Molly Gu [1 ]
Nie, Liming [1 ,3 ]
Niu, Gang [1 ]
Lu, Jie [1 ]
Wang, Wei
Chen, Xiaoyuan [1 ]
机构：
[1] NIBIB, LOMIN, NIH, Bethesda, MD 20892 USA
[2] Cent S Univ, State Key Lab Powder Met, Changsha 410083, Hunan, Peoples R China
[3] Xiamen Univ, Ctr Mol Imaging & Translat Med, State Key Lab Mol Vaccinol & Mol Diagnost, Sch Publ Hlth, Xiamen 361005, Peoples R China
[4] Cent S Univ, Xiangya Hosp 3, Dept Radiol, Changsha 410013, Hunan, Peoples R China
来源：
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2014年 / 136卷 / 23期
基金：
美国国家科学基金会;
关键词：
EARTH FLUORIDE NANOCRYSTALS; PHOTOTHERMAL THERAPY; MULTIFUNCTIONAL NANOPARTICLES; GRAPHENE OXIDE; ULTRASOUND; NANOCAGES; NANORODS; DELIVERY; AGENT; SIZE;
D O I：
10.1021/ja503115n
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
We present a novel gold bellflower (GBF) platform with multiple-branched petals, prepared by a liquid-liquid-gas triphase interface system, for photoacoustic imaging (PAI)-guided photothermal therapy (PTT). Upon near-infrared (NIR) laser irradiation, the GBFs, with strong NIR absorption, showed very strong PA response and an ultrahigh photothermal conversion efficiency (eta, similar to 74% among the reported photothermal conversion agents. The excellent performance in PAI and PTT is mainly attributed to the unique features of the GBFs: (i) multiple-branched petals with an enhanced local electromagnetic field, (ii) long narrow gaps between adjacent petals that induce a strong plasmonic coupling effect, and (iii) a bell-shaped effectively amplify the acoustic signals during the acoustic propagation. Besides the notable PTT and an excellent PAI effect, the NIR-absorbing GBFs may also find applications in NIR light-triggered drug delivery, catalysis, surface enhanced Raman scattering, stealth, antireflection, IR sensors, telecommunications, and the like.
引用
收藏
页码：8307 / 8313
页数：7
相关论文
共 71 条
  • [31] Multifunctional nanoparticles for multimodal imaging and theragnosis
    Lee, Dong-Eun
    Koo, Heebeom
    Sun, In-Cheol
    Ryu, Ju Hee
    Kim, Kwangmeyung
    Kwon, Ick Chan
    [J]. CHEMICAL SOCIETY REVIEWS, 2012, 41 (07) : 2656 - 2672
  • [32] RGD-Conjugated Dendrimer-Modified Gold Nanorods for in Vivo Tumor Targeting and Photothermal Therapy
    Li, Zhiming
    Huang, Peng
    Zhang, Xuejun
    Lin, Jing
    Yang, Sen
    Liu, Bing
    Gao, Feng
    Xi, Peng
    Ren, Qiushi
    Cui, Daxiang
    [J]. MOLECULAR PHARMACEUTICS, 2010, 7 (01) : 94 - 104
  • [33] Photosensitizer-Loaded Gold Vesicles with Strong Plasmonic Coupling Effect for Imaging-Guided Photothermal/Photodynamic Therapy
    Lin, Jing
    Wang, Shouju
    Huang, Peng
    Wang, Zhe
    Chen, Shouhui
    Niu, Gang
    Li, Wanwan
    He, Jie
    Cui, Daxiang
    Lu, Guangming
    Chen, Xiaoyuan
    Nie, Zhihong
    [J]. ACS NANO, 2013, 7 (06) : 5320 - 5329
  • [34] A nanoplasmonic molecular ruler for measuring nuclease activity and DNA footprinting
    Liu, Gang L.
    Yin, Yadong
    Kunchakarra, Siri
    Mukherjee, Bipasha
    Gerion, Daniele
    Jett, Stephen D.
    Bear, David G.
    Gray, Joe W.
    Alivisatos, A. Paul
    Lee, Luke P.
    Chen, Fanqing Frank
    [J]. NATURE NANOTECHNOLOGY, 2006, 1 (01) : 47 - 52
  • [35] Dopamine-Melanin Colloidal Nanospheres: An Efficient Near-Infrared Photothermal Therapeutic Agent for In Vivo Cancer Therapy
    Liu, Yanlan
    Ai, Kelong
    Liu, Jianhua
    Deng, Mo
    He, Yangyang
    Lu, Lehui
    [J]. ADVANCED MATERIALS, 2013, 25 (09) : 1353 - 1359
  • [36] Lovell JF., 2012, Angew Chem Int Ed, V124, P2479
  • [37] Lovell JF, 2011, NAT MATER, V10, P324, DOI [10.1038/NMAT2986, 10.1038/nmat2986]
  • [38] Activatable Photosensitizers for Imaging and Therapy
    Lovell, Jonathan F.
    Liu, Tracy W. B.
    Chen, Juan
    Zheng, Gang
    [J]. CHEMICAL REVIEWS, 2010, 110 (05) : 2839 - 2857
  • [39] Plasmonic Nanobubbles Rapidly Detect and Destroy Drug-Resistant Tumors
    Lukianova-Hleb, Ekaterina Y.
    Ren, Xiaoyang
    Townley, Debra
    Wu, Xiangwei
    Kupferman, Michael E.
    Lapotko, Dmitri O.
    [J]. THERANOSTICS, 2012, 2 (10): : 976 - 987
  • [40] RETRACTED: Tunable Plasmonic Nanoprobes for Theranostics of Prostate Cancer(Retracted article. See vol. 7, pg. 561, 2017)
    Lukianova-Hleb, Ekaterina Y.
    Oginsky, Alexander O.
    Samaniego, Adam P.
    Shenefelt, Derek L.
    Wagner, Daniel S.
    Hafner, Jason H.
    Farach-Carson, Mary C.
    Lapotko, Dmitri O.
    [J]. THERANOSTICS, 2011, 1 : 3 - 17
12345678