Triphase Interface Synthesis of Plasmonic Gold Bellflowers as Near-Infrared Light Mediated Acoustic and Thermal Theranostics

被引：191
作者：
Huang, Peng [1 ]
Rong, Pengfei [1 ,2 ,4 ]
Lin, Jing [1 ]
Li, Wanwan [1 ]
Yan, Xuefeng [1 ]
Zhang, Molly Gu [1 ]
Nie, Liming [1 ,3 ]
Niu, Gang [1 ]
Lu, Jie [1 ]
Wang, Wei
Chen, Xiaoyuan [1 ]
机构：
[1] NIBIB, LOMIN, NIH, Bethesda, MD 20892 USA
[2] Cent S Univ, State Key Lab Powder Met, Changsha 410083, Hunan, Peoples R China
[3] Xiamen Univ, Ctr Mol Imaging & Translat Med, State Key Lab Mol Vaccinol & Mol Diagnost, Sch Publ Hlth, Xiamen 361005, Peoples R China
[4] Cent S Univ, Xiangya Hosp 3, Dept Radiol, Changsha 410013, Hunan, Peoples R China
来源：
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2014年 / 136卷 / 23期
基金：
美国国家科学基金会;
关键词：
EARTH FLUORIDE NANOCRYSTALS; PHOTOTHERMAL THERAPY; MULTIFUNCTIONAL NANOPARTICLES; GRAPHENE OXIDE; ULTRASOUND; NANOCAGES; NANORODS; DELIVERY; AGENT; SIZE;
D O I：
10.1021/ja503115n
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
We present a novel gold bellflower (GBF) platform with multiple-branched petals, prepared by a liquid-liquid-gas triphase interface system, for photoacoustic imaging (PAI)-guided photothermal therapy (PTT). Upon near-infrared (NIR) laser irradiation, the GBFs, with strong NIR absorption, showed very strong PA response and an ultrahigh photothermal conversion efficiency (eta, similar to 74% among the reported photothermal conversion agents. The excellent performance in PAI and PTT is mainly attributed to the unique features of the GBFs: (i) multiple-branched petals with an enhanced local electromagnetic field, (ii) long narrow gaps between adjacent petals that induce a strong plasmonic coupling effect, and (iii) a bell-shaped effectively amplify the acoustic signals during the acoustic propagation. Besides the notable PTT and an excellent PAI effect, the NIR-absorbing GBFs may also find applications in NIR light-triggered drug delivery, catalysis, surface enhanced Raman scattering, stealth, antireflection, IR sensors, telecommunications, and the like.
引用
收藏
页码：8307 / 8313
页数：7
相关论文
共 71 条
[11]   In vivo cancer targeting and imaging with semiconductor quantum dots [J].
Gao, XH ;
Cui, YY ;
Levenson, RM ;
Chung, LWK ;
Nie, SM .
NATURE BIOTECHNOLOGY, 2004, 22 (08) :969-976
[12]   Generating heat with metal nanoparticles [J].
Govorov, Alexander O. ;
Richardson, Hugh H. .
NANO TODAY, 2007, 2 (01) :30-38
[13]   Self-Assembly of Amphiphilic Plasmonic Micelle-Like Nanoparticles in Selective Solvents [J].
He, Jie ;
Huang, Xinglu ;
Li, Yan-Chun ;
Liu, Yijing ;
Babu, Taarika ;
Aronova, Maria A. ;
Wang, Shouju ;
Lu, Zhongyuan ;
Chen, Xiaoyuan ;
Nie, Zhihong .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2013, 135 (21) :7974-7984
[14]   Phase- and Size-Controllable Synthesis of Hexagonal Upconversion Rare-Earth Fluoride Nanocrystals through an Oleic Acid/Ionic Liquid Two-Phase System [J].
He, Meng ;
Huang, Peng ;
Zhang, Chunlei ;
Ma, Jiebing ;
He, Rong ;
Cui, Daxiang .
CHEMISTRY-A EUROPEAN JOURNAL, 2012, 18 (19) :5954-5969
[15]   Dual Phase-Controlled Synthesis of Uniform Lanthanide-Doped NaGdF4 Upconversion Nanocrystals Via an OA/Ionic Liquid Two-Phase System for In Vivo Dual-Modality Imaging [J].
He, Meng ;
Huang, Peng ;
Zhang, Chunlei ;
Hu, Hengyao ;
Bao, Chenchen ;
Gao, Guo ;
He, Rong ;
Cui, Daxiang .
ADVANCED FUNCTIONAL MATERIALS, 2011, 21 (23) :4470-4477
[16]   A general strategy for the synthesis of upconversion rare earth fluoride nanocrystals via a novel OA/ionic liquid two-phase system [J].
He, Meng ;
Huang, Peng ;
Zhang, Chunlei ;
Chen, Feng ;
Wang, Can ;
Ma, Jiebing ;
He, Rong ;
Cui, Daxiang .
CHEMICAL COMMUNICATIONS, 2011, 47 (33) :9510-9512
[17]   Copper Selenide Nanocrystals for Photothermal Therapy [J].
Hessel, Colin M. ;
Pattani, Varun P. ;
Rasch, Michael ;
Panthani, Matthew G. ;
Koo, Bonil ;
Tunnell, James W. ;
Korgel, Brian A. .
NANO LETTERS, 2011, 11 (06) :2560-2566
[18]   Biodegradable Gold Nanovesicles with an Ultrastrong Plasmonic Coupling Effect for Photoacoustic Imaging and Photothermal Therapy [J].
Huang, Peng ;
Lin, Jing ;
Li, Wanwan ;
Rong, Pengfei ;
Wang, Zhe ;
Wang, Shouju ;
Wang, Xiaoping ;
Sun, Xiaolian ;
Aronova, Maria ;
Niu, Gang ;
Leapman, Richard D. ;
Nie, Zhihong ;
Chen, Xiaoyuan .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2013, 52 (52) :13958-13964
[19]   Light-Triggered Theranostics Based on Photosensitizer-Conjugated Carbon Dots for Simultaneous Enhanced-Fluorescence Imaging and Photodynamic Therapy [J].
Huang, Peng ;
Lin, Jing ;
Wang, Xiansong ;
Wang, Zhe ;
Zhang, Chunlei ;
He, Meng ;
Wang, Kan ;
Chen, Feng ;
Li, Zhiming ;
Shen, Guangxia ;
Cui, Daxiang ;
Chen, Xiaoyuan .
ADVANCED MATERIALS, 2012, 24 (37) :5104-5110
[20]   Folic acid-conjugated Silica-modified gold nanorods for X-ray/CT imaging-guided dual-mode radiation and photo-thermal therapy [J].
Huang, Peng ;
Bao, Le ;
Zhang, Chunlei ;
Lin, Jing ;
Luo, Teng ;
Yang, Dapeng ;
He, Meng ;
Li, Zhiming ;
Gao, Guo ;
Gao, Bing ;
Fu, Shen ;
Cui, Daxiang .
BIOMATERIALS, 2011, 32 (36) :9796-9809
12345678