Sn(iv) N-confused porphyrins as photosensitizer dyes for photodynamic therapy in the near IR region

被引：38

作者：

Babu, Balaji ^{[1
]}

Mack, John ^{[1
]}

Nyokong, Tebello ^{[1
]}

机构：

[1] Rhodes Univ, Inst Nanotechnol Innovat, Dept Chem, Makhanda, South Africa

来源：

DALTON TRANSACTIONS | 2020年 / 49卷 / 43期

基金：

新加坡国家研究基金会;

关键词：

MAGNETIC CIRCULAR-DICHROISM; PI-ELECTRON SYSTEMS; SINGLET OXYGEN; COMPLEXES; MECHANISMS; PERIMETER; ISOMER; MODEL;

D O I：

10.1039/d0dt03296d

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The utility of Sn(iv) N-confused porphyrin (SnNCP) for use as photosensitizer dyes in photodynamic therapy is investigated. SnNCP has an unusually high singlet oxygen quantum yield of 0.72 in DMSO. IC50 values of 1.6 and 12.8 mu M were obtained against MCF-7 cells upon irradiation with 660 and 780 nm LEDs.

引用

页码：15180 / 15183

页数：4

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