Serotonin and sleep

被引:229
作者
Ursin, R [1 ]
机构
[1] Univ Bergen, Dept Physiol, N-5009 Bergen, Norway
关键词
serotonin; sleep; REM sleep; dorsal raphe nucleus; serotonergic receptors; microdialysis; 5-HT1A;
D O I
10.1053/smrv.2001.0174
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
For 50 years, serotonin has been in the centre of the search for the mechanisms and control of sleep. Serotonergic neurotransmission is related to the behavioural state of the animal and plays an important role in modulation of the behavioural state, by interacting with other brain areas modulating circadian rhythm, sleep and waking. Serotonergic activity m ay be accompanied by waking or sleep depending on the brain area and receptor type involved in the response, on the current behavioural state and on the concomitant agonism/antagonism of other neurotransmitter systems. (C) 2002 Published by Elsevier Science Ltd.
引用
收藏
页码:57 / 69
页数:13
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