An Expedient Synthesis of Bis-Fused Benzofuran and a Two-Directional Ring-Closing Metathesis for the Synthesis of Bisbenzoxepines and Bisbenzoxocines

被引：18

作者：

Majumdar, Krishna C. ^{[1
]}

Chattopadhyay, Buddhadeb ^{[1
]}

Chakravorty, Santanu ^{[1
]}

机构：

[1] Univ Kalyani, Dept Chem, Kalyani 741235, W Bengal, India

来源：

SYNTHESIS-STUTTGART | 2009年 / 04期

关键词：

palladium catalyst; Grubbs catalyst; intramolecular cyclization; two-directional ring-closing metathesis; 5-exo-trig; benzofuran; oxepine; oxocine; INTRAMOLECULAR HECK REACTION; SEQUENTIAL HOMOBIMETALLIC CATALYSIS; ONE-POT SYNTHESIS; EFFICIENT SYNTHESIS; 2,3-DISUBSTITUTED BENZOFURANS; CLAISEN REARRANGEMENT; STRAIGHTFORWARD SYNTHESIS; REGIOSELECTIVE SYNTHESIS; STEREOSELECTIVE-SYNTHESIS; CYCLIZATION REACTIONS;

D O I：

10.1055/s-0028-1083339

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Synthesis of bis-fused benzofuran derivatives by the implementation of palladium-mediated intramolecular cyclization is described. To our knowledge, this is the first report of the synthesis of bis-fused benzofuran by this protocol. Bisbenzoxepine and bisbenzoxocine derivatives were also synthesized by the application of two-directional ring-closing metathesis.

引用

页码：674 / 680

页数：7

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