A molecularly imprinted nicotine-selective polymer

被引：1

作者：

Matsui, J

Kaneko, A

Miyoshi, Y

Yokoyama, K

Tamiya, E

Takeuchi, T

机构：

[1] HIROSHIMA CITY UNIV, FAC INFORMAT SCI, LAB SYNTHET BIOCHEM, ASAMINAMI KU, NUMATA, HIROSHIMA 73131, JAPAN

[2] JAPAN ADV INST SCI & TECHNOL, TATSUNOKUCHI, ISHIKAWA 92312, JAPAN

来源：

ANALYTICAL LETTERS | 1996年 / 29卷 / 12期

关键词：

molecular imprinting; nicotine; liquid chromatography; polymer;

D O I：

暂无

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A (-)-nicotine-selective polymer was prepared by molecular imprinting technique using methacrylic acid as a functional monomer. Liquid-chromatographic tests, using the polymers as a stationary phase, exhibited that the basicity of the functional group of (-)-nicotine is crucial for rebinding by the molecularly imprinted polymer. Scatchard analysis implied that the binding sites generated within the polymer are heterogeneous in terms of affinity, and the apparent dissociation constant of the highest affinity binding sites was estimated as 3.7 mu M.

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页码：2071 / 2078

页数：8

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