Ribozymes:: Towards gene therapy for alcoholism by silencing the mRNA for mitochondrial aldehyde dehydrogenase (ALDH2)

被引：0
|
作者：
Lobos-Gonzalez, Lorena [1 ]
Munoz-Brauning, Carlos [1 ]
Sapag, Amalia [1 ]
机构：
[1] Univ Chile, Gene Pharmacotherapy Lab, Fac Chem & Pharmaceut Sci, Santiago, Chile
来源：
ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH | 2006年 / 30卷 / 09期
关键词：
D O I：
暂无
中图分类号：
R194 [卫生标准、卫生检查、医药管理];
学科分类号：
摘要：
引用
收藏
页码：155A / 155A
页数：1
相关论文
共 50 条
  • [1] TRANSCRIPTIONAL REGULATION OF THE HUMAN MITOCHONDRIAL ALDEHYDE DEHYDROGENASE (ALDH2) GENE
    STEWART, MJ
    DIPPLE, KM
    CRABB, DW
    CLINICAL RESEARCH, 1994, 42 (02): : A121 - A121
  • [2] Structure Based Inhibition of Mitochondrial Aldehyde Dehydrogenase (ALDH2) Activity
    Kimble-Hill, Ann C.
    Younus, Hina
    Meroueh, Samy
    Hurley, Thomas D.
    BIOPHYSICAL JOURNAL, 2011, 100 (03) : 215 - 215
  • [3] Aldehyde dehydrogenase (ALDH2) activity in hepatoma cells is reduced by an adenoviral vector coding for an ALDH2 antisense mRNA
    Karahanian, E
    Ocaranza, P
    Israel, Y
    ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH, 2005, 29 (08) : 1384 - 1389
  • [4] AAV-Mediated Aldehyde Dehydrogenase 2 (ALDH2) Gene Therapy to Treat Osteoporosis in Ethanol Consuming ALDH2 Deficient Mice
    Camilleri, Anna
    Cung, Michelle
    Pagovich, Odelya E.
    Greenblatt, Matthew B.
    Crystal, Ronald G.
    Stiles, Katie M.
    MOLECULAR THERAPY, 2021, 29 (04) : 175 - 175
  • [5] Assignment of the mitochondrial aldehyde dehydrogenase gene (Aldh2) to mouse chromosome 5 by fluorescence in situ hybridization
    Jeong, KS
    Song, BJ
    Keck-Waggoner, CL
    Huh, CG
    Popescu, NC
    CYTOGENETICS AND CELL GENETICS, 2000, 89 (1-2): : 54 - 55
  • [6] FUNCTIONAL-ANALYSIS OF 5' REGULATORY REGIONS IN THE HUMAN MITOCHONDRIAL ALDEHYDE DEHYDROGENASE (ALDH2) GENE
    STEWART, MJ
    DEDREU, SE
    LITZJACKSON, SL
    CRABB, DW
    HEPATOLOGY, 1995, 22 (04) : 775 - 775
  • [7] CONFIRMATION OF THE ASSIGNMENT OF THE GENE CODING FOR MITOCHONDRIAL ALDEHYDE DEHYDROGENASE (ALDH2) TO HUMAN CHROMOSOME-12
    SMITH, M
    HIROSHIGE, S
    DUESTER, G
    SAXON, P
    CARLOCK, L
    WASMUTH, J
    CYTOGENETICS AND CELL GENETICS, 1985, 40 (1-4): : 748 - 749
  • [8] Hangover symptoms in Asian Americans with variations in the aldehyde dehydrogenase (ALDH2) gene
    Wall, TL
    Horn, SM
    Johnson, ML
    Smith, TL
    Carr, LG
    JOURNAL OF STUDIES ON ALCOHOL, 2000, 61 (01): : 13 - 17
  • [9] Genetic Polymorphisms of the Mitochondrial Aldehyde Dehydrogenase ALDH2 Gene in a Large Ethnic Hakka Population in Southern China
    Zhong, Zhixiong
    Hou, Jingyuan
    Li, Bin
    Zhang, Qifeng
    Li, Cunren
    Liu, Zhidong
    Yang, Min
    Zhong, Wei
    Zhao, Pingsen
    MEDICAL SCIENCE MONITOR, 2018, 24 : 2038 - 2044
  • [10] Cardioprotective effect of piperlonguminin through the activation and stabilization of the mitochondrial aldehyde dehydrogenase ALDH2
    Yoval Sanchez, Belem
    Rodriguez Zavala, Jose
    PROTEIN SCIENCE, 2017, 26 : 88 - 88
12345