Allelic variation in Streptococcus pneumoniae autolysin (N-acetyl muramoyl-L-alanine amidase)

被引：7

作者：

Gillespie, SH ^{[1
]}

McHugh, TD ^{[1
]}

Ayres, H ^{[1
]}

Dickens, A ^{[1
]}

Efstratiou, A ^{[1
]}

Whiting, GC ^{[1
]}

机构：

[1] CENT PUBL HLTH LAB,RESP & SYSTEM INFECT LAB,LONDON NW9 5HT,ENGLAND

来源：

INFECTION AND IMMUNITY | 1997年 / 65卷 / 09期

关键词：

D O I：

10.1128/IAI.65.9.3936-3938.1997

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The lytA gene encoding the autolysin of Streptococcus pneumoniae may be a virulence determinant. Single-strand conformational polymorphism analysis demonstrated heterogenicity throughout the gene in clinical isolates and strains from the clonal serotypes 7 and 14. Sequence analysis of part of the choline-binding domain showed that in two isolates four amino acid substitutions occurred.

引用

页码：3936 / 3938

页数：3

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